Table 2. Alanine scanning library of... | American Society of Hematology

Table 2.

Alanine scanning library of pp65_495-503cytotoxic T-lymphocyte epitope

Peptide name	Position
Peptide name	P1	P2	P3	P4	P5	P6	P7	P8	P9
A1	A	L	V	P	M	V	A	T	V
A2	N	A	V	P	M	V	A	T	V
A3	N	L	A	P	M	V	A	T	V
A4	N	L	V	A	M	V	A	T	V
A5	N	L	V	P	A	V	A	T	V
A6	N	L	V	P	M	A	A	T	V
A7 (native)	N	L	V	P	M	V	A	T	V
A8	N	L	V	P	M	V	A	A	V
A9	N	L	V	P	M	V	A	T	A

Peptide name	Position
Peptide name	P1	P2	P3	P4	P5	P6	P7	P8	P9
A1	A	L	V	P	M	V	A	T	V
A2	N	A	V	P	M	V	A	T	V
A3	N	L	A	P	M	V	A	T	V
A4	N	L	V	A	M	V	A	T	V
A5	N	L	V	P	A	V	A	T	V
A6	N	L	V	P	M	A	A	T	V
A7 (native)	N	L	V	P	M	V	A	T	V
A8	N	L	V	P	M	V	A	A	V
A9	N	L	V	P	M	V	A	T	A

Eight peptide sequences were synthesized with either an amidated or free-acid terminus (either −NH₂ or −COOH) as described in “Materials and methods.” The substitution of a native amino acid for an alanine is shown in bold for each position for the nonamer peptide pp65_495-503. The native sequence corresponds to peptide A7.

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