Table 1. Cell-cycle analysis performed... | American Society of Hematology

Table 1.

Cell-cycle analysis performed by flow cytometry after treatment with ionizing radiation alone or in combination (6 hours before) with tumor necrosis factor–related apoptosis-inducing ligand (1 μg/mL). Analysis was performed 24 hours after irradiation

	HEL		K562		Friend		Erythroleukemic blasts		Normal erythroblasts
	G1	S/G₂-M	G1	S/G₂-M	G1	S/G₂-M	G1	S/G₂-M	G1	S/G₂-M
Control	65	35	58	42	57	43	58	42	54	46
1.5 Gy	37	63	39	61	45	55	46	54	44	56
15 Gy	17	83	33	67	34	66	33	67	42	58
TRAIL	57	43	58	42	55	45	54	46	53	47
1.5 Gy before TRAIL	38	62	39	61	44	56	45	55	43	57
15 Gy before TRAIL	15	85	30	70	35	65	36	64	40	60

	HEL		K562		Friend		Erythroleukemic blasts		Normal erythroblasts
	G1	S/G₂-M	G1	S/G₂-M	G1	S/G₂-M	G1	S/G₂-M	G1	S/G₂-M
Control	65	35	58	42	57	43	58	42	54	46
1.5 Gy	37	63	39	61	45	55	46	54	44	56
15 Gy	17	83	33	67	34	66	33	67	42	58
TRAIL	57	43	58	42	55	45	54	46	53	47
1.5 Gy before TRAIL	38	62	39	61	44	56	45	55	43	57
15 Gy before TRAIL	15	85	30	70	35	65	36	64	40	60

Data represent the means of 2 (erythroleukemic blasts), 4 (HEL, K562, and Friend cell lines) and 5 (normal erythroblasts) separate experiments, performed in duplicate. Fourteen percent of the observations fell within one SD of the means.

TRAIL indicates tumor necrosis factor–related apoptosis-inducing ligand.

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