Table 2.

Binding characteristics of different Malayan Camp cysteine-rich interdomain region 1 mutants

MC CIDR-1 mutant expressed*Positive cells (%)
MC CIDR-1 97.3 ± 1.5 
MC CIDR-1 S203T 97 ± 1.7  
MC CIDR-1 R207N 96 ± 3 
MC CIDR-1 K218T 96.6 ± 2.5 
MC CIDR-1 K235R 94.6 ± 2.5 
MC CIDR-1 K246S 97.6 ± 0.6 
MC CIDR-1 C213-C222 96 ± 2.6 
MC CIDR-1 mutant expressed*Positive cells (%)
MC CIDR-1 97.3 ± 1.5 
MC CIDR-1 S203T 97 ± 1.7  
MC CIDR-1 R207N 96 ± 3 
MC CIDR-1 K218T 96.6 ± 2.5 
MC CIDR-1 K235R 94.6 ± 2.5 
MC CIDR-1 K246S 97.6 ± 0.6 
MC CIDR-1 C213-C222 96 ± 2.6 

MC CIDR-1 mutants were transfected into COS-7 cells and tested for binding to CD36-coated Dynal beads.

For abbreviations, see Table 1.

*

Single-letter amino acid codes shown.

See footnote (marked by an asterisk) to Table 1.

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