Multivariate Cox regression analyses for EFS
. | All patients (n = 113) . | Low risk (n = 64) . | High risk (n = 49) . | |||
---|---|---|---|---|---|---|
RR (95% CI) . | P . | RR (95% CI) . | P . | RR (95% CI) . | P . | |
Risk strata | 2.8 (1.7-4.9) | .0002 | ||||
Patient age | 1 (0.98-1.0) | .83 | 0.99 (0.95-1.0) | .67 | 1 (0.97-1.0) | .94 |
Gender (male) | 1.8 (1.0-3.2) | .04 | 0.82 (0.33-2.1) | .67 | 2 (0.90-4.4) | .091 |
Total cells (×108/kg) | 0.82 (0.52-1.3) | .43 | 0.41 (0.17-1) | .05 | 1.2 (0.6-2.2) | .66 |
CD34+ (×106/kg) | 0.76 (0.59-0.97) | .027 | 0.71 (0.47-1.1) | .10 | 0.84 (0.61-1.2) | .3 |
CD3+(×106/kg) | 1 (0.97-1.0) | .84 | 0.98 (0.93-1.0) | .61 | 1.0 (0.96-1.1) | .62 |
CD3−, CD4+, CD8−(×106/kg) | 2.0 (1.1-4.2) | .03 | 21 (3.5-121) | .0008 | 1.2 (0.51-2.9) | .66 |
. | All patients (n = 113) . | Low risk (n = 64) . | High risk (n = 49) . | |||
---|---|---|---|---|---|---|
RR (95% CI) . | P . | RR (95% CI) . | P . | RR (95% CI) . | P . | |
Risk strata | 2.8 (1.7-4.9) | .0002 | ||||
Patient age | 1 (0.98-1.0) | .83 | 0.99 (0.95-1.0) | .67 | 1 (0.97-1.0) | .94 |
Gender (male) | 1.8 (1.0-3.2) | .04 | 0.82 (0.33-2.1) | .67 | 2 (0.90-4.4) | .091 |
Total cells (×108/kg) | 0.82 (0.52-1.3) | .43 | 0.41 (0.17-1) | .05 | 1.2 (0.6-2.2) | .66 |
CD34+ (×106/kg) | 0.76 (0.59-0.97) | .027 | 0.71 (0.47-1.1) | .10 | 0.84 (0.61-1.2) | .3 |
CD3+(×106/kg) | 1 (0.97-1.0) | .84 | 0.98 (0.93-1.0) | .61 | 1.0 (0.96-1.1) | .62 |
CD3−, CD4+, CD8−(×106/kg) | 2.0 (1.1-4.2) | .03 | 21 (3.5-121) | .0008 | 1.2 (0.51-2.9) | .66 |
Separate analyses were performed for the entire group of patients (n = 113) and the subsets of low-risk (n = 64) and high-risk (n = 49) patients. All covariates listed were entered into the multivariate Cox model. Significant (P < .05) associations of covariates with EFS are in bold.