Multivariate Cox regression analyses of nonrelapse deaths
. | All patients (n = 113) . | Low risk (n = 64) . | High risk (n = 49) . | |||
---|---|---|---|---|---|---|
RR (95% CI) . | P . | RR (95% CI) . | P . | RR (95% CI) . | P . | |
Risk strata | 2.3 (1.1-4.7) | .02 | ||||
Patient age | 1.1 (1.0-1.1) | .002 | 1.03 (0.97-1.1) | .32 | 1.1 (1.0-1.1) | .0018 |
Gender (male) | 1.6 (0.69-3.8) | .26 | 0.77 (0.25-2.4) | .65 | 2 (0.78-16.6) | .10 |
Total cells (×108/kg) | 1.1 (0.54-2.1) | .84 | 0.62 (0.19-2) | .42 | 1.2 (0.66-4.2) | .28 |
CD34+(×106/kg) | 0.58 (0.39-0.84) | .0042 | 0.63 (0.36-1.1) | .10 | 0.51 (0.29-0.89) | .012 |
CD3+ (×106/kg) | 1 (0.95-1.1) | .97 | 0.98 (0.91-1.1) | .64 | 1.0 (0.93-1.1) | .90 |
CD3−, CD4+, CD8− (×106/kg) | 2.2 (0.83-5.6) | .11 | 7.3 (0.89-60) | .065 | 2.1 (0.65-7) | .21 |
. | All patients (n = 113) . | Low risk (n = 64) . | High risk (n = 49) . | |||
---|---|---|---|---|---|---|
RR (95% CI) . | P . | RR (95% CI) . | P . | RR (95% CI) . | P . | |
Risk strata | 2.3 (1.1-4.7) | .02 | ||||
Patient age | 1.1 (1.0-1.1) | .002 | 1.03 (0.97-1.1) | .32 | 1.1 (1.0-1.1) | .0018 |
Gender (male) | 1.6 (0.69-3.8) | .26 | 0.77 (0.25-2.4) | .65 | 2 (0.78-16.6) | .10 |
Total cells (×108/kg) | 1.1 (0.54-2.1) | .84 | 0.62 (0.19-2) | .42 | 1.2 (0.66-4.2) | .28 |
CD34+(×106/kg) | 0.58 (0.39-0.84) | .0042 | 0.63 (0.36-1.1) | .10 | 0.51 (0.29-0.89) | .012 |
CD3+ (×106/kg) | 1 (0.95-1.1) | .97 | 0.98 (0.91-1.1) | .64 | 1.0 (0.93-1.1) | .90 |
CD3−, CD4+, CD8− (×106/kg) | 2.2 (0.83-5.6) | .11 | 7.3 (0.89-60) | .065 | 2.1 (0.65-7) | .21 |
Separate analyses were performed for the entire group of patients (n = 113) and the subsets of low-risk (n = 64) and high-risk (n = 49) patients. All covariates listed were entered into the multivariate Cox model. Significant (P < .05) associations of covariates with EFS are in bold.