Results of T-cell αβ receptor panel analysis
. | Vα2 . | Vα12.1 . | Vβ3.1 . | Vβ5(a) . | Vβ5(b) . | Vβ5(c) . | Vβ6.7 . | Vβ8(a) . | Vβ12 . | Vβ13 (%) . |
---|---|---|---|---|---|---|---|---|---|---|
T line of patient 1 | 5.2 | 3.8 | 53.5 | 56.5 | 3.7 | 5.3 | 4.3 | 3.7 | 4.9 | 8.6 |
T line of patient 2 | < 1.0 | < 1.0 | < 1.0 | > 95.0 | < 1.0 | < 1.0 | < 1.0 | < 1.0 | < 1.0 | < 1.0 |
Control PBMC | 2.5 | 2.1 | 5.1 | 8.0 | 1.0 | 3.5 | 1.6 | 3.5 | 2.6 | 3.5 |
. | Vα2 . | Vα12.1 . | Vβ3.1 . | Vβ5(a) . | Vβ5(b) . | Vβ5(c) . | Vβ6.7 . | Vβ8(a) . | Vβ12 . | Vβ13 (%) . |
---|---|---|---|---|---|---|---|---|---|---|
T line of patient 1 | 5.2 | 3.8 | 53.5 | 56.5 | 3.7 | 5.3 | 4.3 | 3.7 | 4.9 | 8.6 |
T line of patient 2 | < 1.0 | < 1.0 | < 1.0 | > 95.0 | < 1.0 | < 1.0 | < 1.0 | < 1.0 | < 1.0 | < 1.0 |
Control PBMC | 2.5 | 2.1 | 5.1 | 8.0 | 1.0 | 3.5 | 1.6 | 3.5 | 2.6 | 3.5 |
The clonality of T lines from patients 1 and 2 was studied by T-cell receptor panel analysis described in “Materials and methods.” Peripheral blood mononuclear cells (PBMC) from healthy individuals were used as controls.