Table 3.

Donor recipient HLA compatibility and disparities among the 3 types of transplant; nonmanipulated unrelated bone marrow (UBMT), T-cell–depleted unrelated bone marrow donor (T-UBMT), and umbilical unrelated cord blood recipients (UCBT)

HLA typingUBMT (n = 262)T-UBMT (n = 180)UCBT (n = 99)P value4-150
A (serology)     
 Matched 252  (96%) 146  (81%) 64  (65%) .0001  
 1 difference 10  (4%) 34  (19%) 35  (35%)  
B (serology)     
 Matched 254  (97%) 144  (80%) 50  (51%)  
 1 difference 8  (3%) 34  (19%) 44  (44%) .0001  
 2 differences 2  (1%) 5  (5%)  
DRB1 (allelic typing)     
 Matched 229  (89%) 149  (88%) 50  (51%)  
 1 difference 28  (11%) 21  (12%) 40  (41%)  
 2 differences 1  (0.4%) 8  (8%) .0001 
 missing 10  
HLA typingUBMT (n = 262)T-UBMT (n = 180)UCBT (n = 99)P value4-150
A (serology)     
 Matched 252  (96%) 146  (81%) 64  (65%) .0001  
 1 difference 10  (4%) 34  (19%) 35  (35%)  
B (serology)     
 Matched 254  (97%) 144  (80%) 50  (51%)  
 1 difference 8  (3%) 34  (19%) 44  (44%) .0001  
 2 differences 2  (1%) 5  (5%)  
DRB1 (allelic typing)     
 Matched 229  (89%) 149  (88%) 50  (51%)  
 1 difference 28  (11%) 21  (12%) 40  (41%)  
 2 differences 1  (0.4%) 8  (8%) .0001 
 missing 10  
F4-150

Fisher test.

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