Donor recipient HLA compatibility and disparities among the 3 types of transplant; nonmanipulated unrelated bone marrow (UBMT), T-cell–depleted unrelated bone marrow donor (T-UBMT), and umbilical unrelated cord blood recipients (UCBT)
HLA typing . | UBMT (n = 262) . | T-UBMT (n = 180) . | UCBT (n = 99) . | P value4-150 . |
---|---|---|---|---|
A (serology) | ||||
Matched | 252 (96%) | 146 (81%) | 64 (65%) | .0001 |
1 difference | 10 (4%) | 34 (19%) | 35 (35%) | |
B (serology) | ||||
Matched | 254 (97%) | 144 (80%) | 50 (51%) | |
1 difference | 8 (3%) | 34 (19%) | 44 (44%) | .0001 |
2 differences | 0 | 2 (1%) | 5 (5%) | |
DRB1 (allelic typing) | ||||
Matched | 229 (89%) | 149 (88%) | 50 (51%) | |
1 difference | 28 (11%) | 21 (12%) | 40 (41%) | |
2 differences | 1 (0.4%) | 0 | 8 (8%) | .0001 |
missing | 4 | 10 | 1 |
HLA typing . | UBMT (n = 262) . | T-UBMT (n = 180) . | UCBT (n = 99) . | P value4-150 . |
---|---|---|---|---|
A (serology) | ||||
Matched | 252 (96%) | 146 (81%) | 64 (65%) | .0001 |
1 difference | 10 (4%) | 34 (19%) | 35 (35%) | |
B (serology) | ||||
Matched | 254 (97%) | 144 (80%) | 50 (51%) | |
1 difference | 8 (3%) | 34 (19%) | 44 (44%) | .0001 |
2 differences | 0 | 2 (1%) | 5 (5%) | |
DRB1 (allelic typing) | ||||
Matched | 229 (89%) | 149 (88%) | 50 (51%) | |
1 difference | 28 (11%) | 21 (12%) | 40 (41%) | |
2 differences | 1 (0.4%) | 0 | 8 (8%) | .0001 |
missing | 4 | 10 | 1 |
Fisher test.