Characteristics of patients with adult T-cell leukemia/lymphoma, according to number of chromosomal imbalances per patient
| Characteristic . | 0-2 Imbalances (n = 27) . | > 2 Imbalances (n = 37) . | P value . |
|---|---|---|---|
| Sex, M/F | 17/10 | 30/7 | Not significant |
| Mean ± SD age, y | 53.4 ± 11.6 | 59.2 ± 11.6 | .04 |
| Performance status, 0/1/2 or 3/4 | 9/14/2/2 | 4/6/21/6 | < .0001 |
| Total involved lesion, 1/2 or 3/≥4 | 8/13/6 | 3/7/27 | .0003 |
| Mean ± SD lactic acid dehydrogenase, μ/mL | 492 ± 263 | 1676 ± 1894 | < .0001 |
| Corrected calcium value, < 2.74 mM per L/≥ 2.74 mM per L | 2/25 | 14/23 | .006 |
| Clinical subtype, aggressive/indolent | 13/14 | 33/4 | .0003 |
| Immunophenotype, CD4+8−/unusual | 26/1 | 30/7 | .07 |
| Characteristic . | 0-2 Imbalances (n = 27) . | > 2 Imbalances (n = 37) . | P value . |
|---|---|---|---|
| Sex, M/F | 17/10 | 30/7 | Not significant |
| Mean ± SD age, y | 53.4 ± 11.6 | 59.2 ± 11.6 | .04 |
| Performance status, 0/1/2 or 3/4 | 9/14/2/2 | 4/6/21/6 | < .0001 |
| Total involved lesion, 1/2 or 3/≥4 | 8/13/6 | 3/7/27 | .0003 |
| Mean ± SD lactic acid dehydrogenase, μ/mL | 492 ± 263 | 1676 ± 1894 | < .0001 |
| Corrected calcium value, < 2.74 mM per L/≥ 2.74 mM per L | 2/25 | 14/23 | .006 |
| Clinical subtype, aggressive/indolent | 13/14 | 33/4 | .0003 |
| Immunophenotype, CD4+8−/unusual | 26/1 | 30/7 | .07 |