Detection of male donor WBCs after transfusion of red blood cells to female subjects
| Recipient . | First transfusion episode (T1) . | Transfusion interval (start of T1 to start of T2) . | Second transfusion episode (T2) . | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Donor gender: component age (d) . | Cell count (male cells/mL recipient blood) . | Donor gender: component age (d) . | Cell count (male cells/mL recipient blood) . | ||||||||||
| Pre . | D7 . | D14 . | D21 . | D28 . | Pre . | D7 . | D14 . | D21 . | D28 . | ||||
| NLR-1 | M:10; F:7 | 0, 0 | 8, 0 | (NT)† | (NT)† | (NT)† | 13 days | M:12; F:12 | 0, 0 | 64, 71.5 | 0, 0 | 0, 0 | 0, 0 |
| NLR-2 | M:3; M:5 | 0 | NT | 0 | 0 | (NT)† | 22 days | M:3; M:3 | 0, 0; 0 | 25, 55; 20 | 0, 0; 0 | NT | NT |
| NLR-3 | M:7; F:7 | 0 | NT | 0 | 0 | 0 | 66 days | M:7; F:10 | 0, 0 | 23; 49‡ | NT | NT | NT |
| NLR-4 | M:24; F:24 | 0, 0 | 0, 0 | 1830, 2110 | 16, 0 | 0, 0 | 70 days | M:11; F:11 | 0 | 0 | 0 | 0 | NT |
| NLR-5 | M:12; F:12* | 0, 0; 0 | NT | 0, 0; 16, 0 | 17, 5; 15 | 9, 21; 0 | 61 days | M:3; M:4 | 0, 0; 0 | 16.5, 362 | 0, 20; 10 | 8.5, 31 | 0, 0; 0 |
| LR-1 | M:7; M:10; M:13; F:3 | 0 | 0 | 0 | 0 | 02-153 | No second transfusion | ||||||
| Recipient . | First transfusion episode (T1) . | Transfusion interval (start of T1 to start of T2) . | Second transfusion episode (T2) . | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Donor gender: component age (d) . | Cell count (male cells/mL recipient blood) . | Donor gender: component age (d) . | Cell count (male cells/mL recipient blood) . | ||||||||||
| Pre . | D7 . | D14 . | D21 . | D28 . | Pre . | D7 . | D14 . | D21 . | D28 . | ||||
| NLR-1 | M:10; F:7 | 0, 0 | 8, 0 | (NT)† | (NT)† | (NT)† | 13 days | M:12; F:12 | 0, 0 | 64, 71.5 | 0, 0 | 0, 0 | 0, 0 |
| NLR-2 | M:3; M:5 | 0 | NT | 0 | 0 | (NT)† | 22 days | M:3; M:3 | 0, 0; 0 | 25, 55; 20 | 0, 0; 0 | NT | NT |
| NLR-3 | M:7; F:7 | 0 | NT | 0 | 0 | 0 | 66 days | M:7; F:10 | 0, 0 | 23; 49‡ | NT | NT | NT |
| NLR-4 | M:24; F:24 | 0, 0 | 0, 0 | 1830, 2110 | 16, 0 | 0, 0 | 70 days | M:11; F:11 | 0 | 0 | 0 | 0 | NT |
| NLR-5 | M:12; F:12* | 0, 0; 0 | NT | 0, 0; 16, 0 | 17, 5; 15 | 9, 21; 0 | 61 days | M:3; M:4 | 0, 0; 0 | 16.5, 362 | 0, 20; 10 | 8.5, 31 | 0, 0; 0 |
| LR-1 | M:7; M:10; M:13; F:3 | 0 | 0 | 0 | 0 | 02-153 | No second transfusion | ||||||
Male donor cells were considered present in a specimen (shaded box) if all replicate test results were >0 and at least one of the results was ≥25 donor cells/mL. Results separated by commas represent replicates of the same specimen tube. Results separated by semicolon represent repeat testing on separate specimen tubes (results are listed in order of testing).
Subject NLR-5 also received 2 U RBCs (M:16; F15) 9 days after the T1 transfusion.
See T2.
Subject NLR-3. T2 day 4 results also available: 90, 241.
Subject LR-1. At 3 months after T1, male cells were detected: 33, 40.
NT, not tested.