Frequency of BCL-2/JHtranslocation in peripheral blood lymphocytes of Japanese and German individuals
| Age (y) . | Japanese individuals . | German individuals . | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0-19 . | 20-39 . | 40-59 . | 60-79 . | > 80 . | Total . | 0-19 . | 20-39 . | 40-59 . | 60-79 . | > 80 . | Total . | |
| Positive number/total number examined* | 1/49 | 9/45 | 8/46 | 15/65 | 6/36 | 39/241 | NT | 11/22 | 23/43 | 5/10 | NT | 39/75† |
| Frequency of positive result (%) | 2.0 | 20.0 | 17.3 | 23.1 | 16.7 | 16.2 | — | 50.0 | 53.5 | 50.0 | — | 52.0 |
| Multiple translocation/positive number‡ | 0/1 | 1/9 | 2/8 | 2/15 | 1/6 | 6/39 (15.4%) | — | 4/11 | 11/23 | 2/5 | — | 17/391-153 (43.6%) |
| Age (y) . | Japanese individuals . | German individuals . | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0-19 . | 20-39 . | 40-59 . | 60-79 . | > 80 . | Total . | 0-19 . | 20-39 . | 40-59 . | 60-79 . | > 80 . | Total . | |
| Positive number/total number examined* | 1/49 | 9/45 | 8/46 | 15/65 | 6/36 | 39/241 | NT | 11/22 | 23/43 | 5/10 | NT | 39/75† |
| Frequency of positive result (%) | 2.0 | 20.0 | 17.3 | 23.1 | 16.7 | 16.2 | — | 50.0 | 53.5 | 50.0 | — | 52.0 |
| Multiple translocation/positive number‡ | 0/1 | 1/9 | 2/8 | 2/15 | 1/6 | 6/39 (15.4%) | — | 4/11 | 11/23 | 2/5 | — | 17/391-153 (43.6%) |
NT indicates not tested.
The values represent the number of samples showing positive results/the number of samples tested in each age group.
The value (39/75) in German individuals is significantly higher than that of Japanese samples obtained from individuals aged 20 to 79 years (32/156) (P < .0001).
The values represent the number of samples showing multiple break points/the number of positive samples in each age group.
The value (17/39) in German individuals is significantly higher than that in Japanese individuals (6/39) (P < .01).