Sequences selected on monoclonal antibody 6B4 using both a L15 and a C7 (*) phage peptide library.
| 6B4 clones . | Peptide . |
|---|---|
| A2, E4 | CNKPGERTC* |
| G12, D7, B4 | CDTLKPGEC* |
| A11, D10 | CADQKPGEC* |
| D3 | CYKPGEWAC* |
| H9 | CKPGEVQQC* |
| E3 | CKPVENRAC* |
| D9, F5, B5 | KPGEMR |
| G3 | KPGEMRGAA |
| E8, A9 | KPGDPSALHVVRCWIC |
| GPIb 251-273 | SDKFPVYKYPGKGCPTLGDEGDT |
| E1 | DGRRDVVVRSATFYL |
| D12 | EGLYSPWWPRSLPVL |
| D3 | SSKTRSFGVHLVGPY |
| A12 | LPPGLHVFPLASNRS |
| GPIb 223-245 | NAENVYVWKQG˙VDVKAM˙TSNVAS |
| 6B4 clones . | Peptide . |
|---|---|
| A2, E4 | CNKPGERTC* |
| G12, D7, B4 | CDTLKPGEC* |
| A11, D10 | CADQKPGEC* |
| D3 | CYKPGEWAC* |
| H9 | CKPGEVQQC* |
| E3 | CKPVENRAC* |
| D9, F5, B5 | KPGEMR |
| G3 | KPGEMRGAA |
| E8, A9 | KPGDPSALHVVRCWIC |
| GPIb 251-273 | SDKFPVYKYPGKGCPTLGDEGDT |
| E1 | DGRRDVVVRSATFYL |
| D12 | EGLYSPWWPRSLPVL |
| D3 | SSKTRSFGVHLVGPY |
| A12 | LPPGLHVFPLASNRS |
| GPIb 223-245 | NAENVYVWKQG˙VDVKAM˙TSNVAS |
Amino acids identical with GPIbα residues are italic, peptides of GPIbα studied in Vicente et al8 are underlined, PT-vWD mutations G233V and M239V are marked by ·.
GPIb indicates glycoprotein Ib; PT-vWD, platelet-type von Willebrand disease.