Table 1.

NF-κB activity in Tax transgenic mouse tissues

TissueOptical density1-153
Peripheral tumors* 0.493 ± 0.186 
Splenocytes 0.140 ± 0.012  
Control tissues 0.015 ± 0.010 
TissueOptical density1-153
Peripheral tumors* 0.493 ± 0.186 
Splenocytes 0.140 ± 0.012  
Control tissues 0.015 ± 0.010 
*

Nuclear extracts were prepared from 6 peripheral tumors from 6 different animals, of which 5 tumors arose on an extremity and 1 tumor arose on the nose.

Nuclear extracts were prepared from uncultured splenocytes of 3 different animals.

Nuclear extracts were prepared from 4 tissues from 2 animals (from heart, 2 kidneys, and brain).

F1-153

p50-p65 NF-κB DNA binding activity was measured in an ELISA format. Means and standard deviations are listed.

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