Patients' main clinical characteristics at diagnosis
| Case no. . | Age (y) . | Sex . | ECOG PS . | Ann Arbor stage . | Nodal sites of involvement . | Extramodal sites of involvement . | Site of diagnostic biopsy . | LDH . | β-2 microglobulin . | AbHCVs . | Serum monoclonal immunoglobulins . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 45 | F | 0 | IV A | Cervical, axillary, mediastinal, para-aortic, iliac | Bone marrow | Inguinal node | NA | NA | NA | Absent |
| 2 | 50 | M | 0 | IV A | Mediastinal, coeliac, para-aortic, axillary | Bone marrow | Axillary node | Normal | Elevated | − | Absent |
| 3 | 69 | M | 0 | IV A | Cervical, supraclavicular, mediastinal | Bone marrow | Supraclavicular node | Normal | NA | NA | Absent |
| 4 | 64 | M | 0 | IV A | Inguinal, axillary, mediastinal | Spleen, bone marrow | Inguinal node | Elevated | Elevated | + | IgMκ = 0.5 g/dL |
| 5 | 42 | F | 0 | III A | Inguinal, iliac, lombo-aortic | None | Axillary node | Normal | Normal | − | Absent |
| 6 | 68 | F | 0 | III A | Mediastinal, axillary, cervical | Spleen | Axillary node | Normal | NA | − | Absent |
| 7 | 68 | M | 0 | IV A | Supraclavicular, cervical, axillary | Spleen, bone marrow | Supraclavicular node | Normal | Normal | − | IgGλ = 1.1 g/dL |
| 8 | 50 | M | 0 | II A | Retroperitoneal | None | Retroperitoneal node | Normal | NA | − | IgMλ = 0.4 g/dL |
| Case no. . | Age (y) . | Sex . | ECOG PS . | Ann Arbor stage . | Nodal sites of involvement . | Extramodal sites of involvement . | Site of diagnostic biopsy . | LDH . | β-2 microglobulin . | AbHCVs . | Serum monoclonal immunoglobulins . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 45 | F | 0 | IV A | Cervical, axillary, mediastinal, para-aortic, iliac | Bone marrow | Inguinal node | NA | NA | NA | Absent |
| 2 | 50 | M | 0 | IV A | Mediastinal, coeliac, para-aortic, axillary | Bone marrow | Axillary node | Normal | Elevated | − | Absent |
| 3 | 69 | M | 0 | IV A | Cervical, supraclavicular, mediastinal | Bone marrow | Supraclavicular node | Normal | NA | NA | Absent |
| 4 | 64 | M | 0 | IV A | Inguinal, axillary, mediastinal | Spleen, bone marrow | Inguinal node | Elevated | Elevated | + | IgMκ = 0.5 g/dL |
| 5 | 42 | F | 0 | III A | Inguinal, iliac, lombo-aortic | None | Axillary node | Normal | Normal | − | Absent |
| 6 | 68 | F | 0 | III A | Mediastinal, axillary, cervical | Spleen | Axillary node | Normal | NA | − | Absent |
| 7 | 68 | M | 0 | IV A | Supraclavicular, cervical, axillary | Spleen, bone marrow | Supraclavicular node | Normal | Normal | − | IgGλ = 1.1 g/dL |
| 8 | 50 | M | 0 | II A | Retroperitoneal | None | Retroperitoneal node | Normal | NA | − | IgMλ = 0.4 g/dL |
ECOG PS indicates Eastern Cooperative Oncology Group performance status; LDH, lactate dehydrogenase; AbHCVs, anti–hepatitis C virus antibodies; NA, not assessed; Ig, immunoglobulin.