Table 6. Monitoring of immunologic... | American Society of Hematology

Table 6.

Monitoring of immunologic parameters

Case no.	C3, mg/dL			Serum IgG, mg/dL			Serum IgM, mg/dL			PAIgG, ng/10⁶ platelets			(CD19⁺) B cells, × 10⁶/L
Case no.	Baseline	Nadir	At 48 wk	Baseline	Nadir	At 48 wk	Baseline	Nadir	At 48 wk	Baseline	Nadir	At 48 wk	Baseline	Nadir	At 48 wk
1	93	88	97	1235	1037	1120	189	156	174	141	102	158	265	10	210
2	115	102	138	964	885	1078	157	91	126	ND	ND	ND	310	5	376
3	101	96	99	1641	1290	1476	220	138	242	298	276	342	62	3	96
4	76	38	92	727	575	842	86	52	71	459	315	387	123	11	179
5	132	125	147	1190	1165	1327	147	128	193	167	3	5	104	6	158
6	ND	ND	ND	1320	981	1252	243	105	1272	ND	ND	ND	ND	ND	ND
7	94	75	81	1050	733	977	175	74	110	382	364	335	418	26	295
8	158	79	79	863	605	912	204	98	183	85	10	14	82	4	106
9	131	122	168	1267	880	1125	113	104	238	ND	ND	ND	259	6	185
10	62	40	122	1315	1171	1263	197	154	186	649	8	21	324	7	252
11	80	82	135	984	848	920	236	129	164	215	4	106	128	9	105
12	119	87	110	1100	836	1057	258	87	134	ND	ND	ND	189	8	176
13	133	101	128	1548	1316	1391	186	159	171	294	231	270	213	18	134
14	157	56	129	1491	1284	1342	264	235	270	452	2	6	238	7	296
15	ND	ND	ND	1050	825	936	129	104	163	298	263	312	56	5	72
16	125	96	109	1732	1362	1459	184	166	219	190	157	276	202	12	166
17	142	120	131	1256	954	1173	328	112	178	337	8	174	146	9	121
18	138	113	154	895	840	1066	182	176	244	848	536	901	78	6	105
19	110	91	127	1071	483	738	145	65	106	249	7	10	304	10	260
20	ND	ND	ND	ND	945	1053	ND	156	217	515	342	437	221	15	143
21	86	54	93	1420	1308	1395	233	186	225	ND	ND	ND	ND	ND	ND
22	145	130	163	820	673	744	171	128	206	271	180	239	95	8	67
23	169	120	151	1346	1158	1274	202	194	246	134	117	126	164	4	112
24	107	90	96	1189	976	1060	95	74	114	75	5	27	242	9	281
25	ND	ND	ND	ND	1264	1381	ND	146	177	ND	ND	ND	137	3	174

Case no.	C3, mg/dL			Serum IgG, mg/dL			Serum IgM, mg/dL			PAIgG, ng/10⁶ platelets			(CD19⁺) B cells, × 10⁶/L
Case no.	Baseline	Nadir	At 48 wk	Baseline	Nadir	At 48 wk	Baseline	Nadir	At 48 wk	Baseline	Nadir	At 48 wk	Baseline	Nadir	At 48 wk
1	93	88	97	1235	1037	1120	189	156	174	141	102	158	265	10	210
2	115	102	138	964	885	1078	157	91	126	ND	ND	ND	310	5	376
3	101	96	99	1641	1290	1476	220	138	242	298	276	342	62	3	96
4	76	38	92	727	575	842	86	52	71	459	315	387	123	11	179
5	132	125	147	1190	1165	1327	147	128	193	167	3	5	104	6	158
6	ND	ND	ND	1320	981	1252	243	105	1272	ND	ND	ND	ND	ND	ND
7	94	75	81	1050	733	977	175	74	110	382	364	335	418	26	295
8	158	79	79	863	605	912	204	98	183	85	10	14	82	4	106
9	131	122	168	1267	880	1125	113	104	238	ND	ND	ND	259	6	185
10	62	40	122	1315	1171	1263	197	154	186	649	8	21	324	7	252
11	80	82	135	984	848	920	236	129	164	215	4	106	128	9	105
12	119	87	110	1100	836	1057	258	87	134	ND	ND	ND	189	8	176
13	133	101	128	1548	1316	1391	186	159	171	294	231	270	213	18	134
14	157	56	129	1491	1284	1342	264	235	270	452	2	6	238	7	296
15	ND	ND	ND	1050	825	936	129	104	163	298	263	312	56	5	72
16	125	96	109	1732	1362	1459	184	166	219	190	157	276	202	12	166
17	142	120	131	1256	954	1173	328	112	178	337	8	174	146	9	121
18	138	113	154	895	840	1066	182	176	244	848	536	901	78	6	105
19	110	91	127	1071	483	738	145	65	106	249	7	10	304	10	260
20	ND	ND	ND	ND	945	1053	ND	156	217	515	342	437	221	15	143
21	86	54	93	1420	1308	1395	233	186	225	ND	ND	ND	ND	ND	ND
22	145	130	163	820	673	744	171	128	206	271	180	239	95	8	67
23	169	120	151	1346	1158	1274	202	194	246	134	117	126	164	4	112
24	107	90	96	1189	976	1060	95	74	114	75	5	27	242	9	281
25	ND	ND	ND	ND	1264	1381	ND	146	177	ND	ND	ND	137	3	174

Normal values are: C3, 60-180 mg/dL; serum IgG, 800-1800 mg/dL; serum IgM, 60-280 mg/dL; PAIgG, 0-10 ng/10⁶ platelets; (CD19⁺) B cells, 35-350 × 10⁶/L.

ND indicates not done.

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