Peripheral blood values from mice aged 8 to 10 weeks
| Genotype . | n . | CBC Values‡ . | ||||
|---|---|---|---|---|---|---|
| RBCs (1012/L) . | WBCs (109/L) . | Hgb (g/L) . | PLTs (109/L) . | MCV (fL) . | ||
| Fancc+/+Sod1+/+ | 15 | 10.02 ± 0.27 | 3.69 ± 1.09 | 163.4 ± 4.47 | 605.3 ± 47.2 | 52.8 ± 0.69 |
| Fancc+/−Sod1+/− | 18 | 9.66 ± 0.27 | 6.59 ± 0.86 | 161.9 ± 4.50 | 708 ± 49.3 | 52.3 ± 0.62 |
| Fancc−/− | 9 | 9.68 ± 0.20 | 1.55 ± 0.23 | 158.6 ± 4.05 | 435 ± 26.9* | 53.5 ± 0.42 |
| Sod1−/− | 10 | 8.72 ± 0.42* | 1.94 ± 0.56 | 147 ± 3.96* | 745.5 ± 49.1 | 54.1 ± 1.0 |
| Fancc−/−Sod1−/− | 9 | 7.9 ± 0.36† | 0.96 ± 0.20* | 136 ± 4.52† | 719 ± 93.7 | 58.5 ± 0.68† |
| Genotype . | n . | CBC Values‡ . | ||||
|---|---|---|---|---|---|---|
| RBCs (1012/L) . | WBCs (109/L) . | Hgb (g/L) . | PLTs (109/L) . | MCV (fL) . | ||
| Fancc+/+Sod1+/+ | 15 | 10.02 ± 0.27 | 3.69 ± 1.09 | 163.4 ± 4.47 | 605.3 ± 47.2 | 52.8 ± 0.69 |
| Fancc+/−Sod1+/− | 18 | 9.66 ± 0.27 | 6.59 ± 0.86 | 161.9 ± 4.50 | 708 ± 49.3 | 52.3 ± 0.62 |
| Fancc−/− | 9 | 9.68 ± 0.20 | 1.55 ± 0.23 | 158.6 ± 4.05 | 435 ± 26.9* | 53.5 ± 0.42 |
| Sod1−/− | 10 | 8.72 ± 0.42* | 1.94 ± 0.56 | 147 ± 3.96* | 745.5 ± 49.1 | 54.1 ± 1.0 |
| Fancc−/−Sod1−/− | 9 | 7.9 ± 0.36† | 0.96 ± 0.20* | 136 ± 4.52† | 719 ± 93.7 | 58.5 ± 0.68† |
Values represent average ± SEM for the indicated number of animals per group.
RBC indicates red blood cells; WBC, white blood cells; CBC, complete blood count; Hgb, hemoglobin; PLTs, platelets; MCV, mean cell volume.
P < .05.
P < .0005.
CBCs were quantified using a Sysmex 9500 automated blood analyser.