Hematology values
| . | Placebo (n = 83) . | PEG-rHuMGDF 1 μg/kg (n = 18) . | PEG-rHuMGDF 3 μg/kg (n = 65) . | PEG-rHuMGDF combined (n = 83) . |
|---|---|---|---|---|
| Before transfusion | ||||
| Platelet count (× 109/L) | 11 (2-33) | 11 (4-20) | 11 (1-43) | 11 (1-43) |
| WBC (× 109/L) | 0.4 (0.1-44) | 0.8 (0.2-11) | 0.6 (0.05-40) | 0.6 (0.05-40) |
| Hematocrit (%) | 26 (17-35) | 26 (14-32) | 24 (20-33) | 25 (14-33) |
| Posttransfusion absolute platelet count increment (× 109/L) | ||||
| Early (1-4 h) | 19 (−12-66) | 41 (5-133) | 82 (−4-188) | 61 (−4-188) |
| Late (18-24 h) | 8 (−9-50) | 25 (−1-74) | 52 (−4-137) | 41 (−4-137) |
| Posttransfusion platelet count (× 109/L) | ||||
| Maximum | 32 (4-216) | 52 (16-143) | 93 (2-192) | 77 (2-192) |
| Early (1-4 h) | 31 (3-76) | 52 (14-143) | 92 (2-192) | 74 (2-192) |
| More than 50 × 109/L (%)3-150 | 18 | 56 | 77 | 72 |
| More than 75 × 109/L (%)3-150 | 1 | 11 | 60 | 49 |
| Late (18-24 h) | 22 (4-66) | 35 (10-84) | 66 (1-148) | 52 (1-148) |
| . | Placebo (n = 83) . | PEG-rHuMGDF 1 μg/kg (n = 18) . | PEG-rHuMGDF 3 μg/kg (n = 65) . | PEG-rHuMGDF combined (n = 83) . |
|---|---|---|---|---|
| Before transfusion | ||||
| Platelet count (× 109/L) | 11 (2-33) | 11 (4-20) | 11 (1-43) | 11 (1-43) |
| WBC (× 109/L) | 0.4 (0.1-44) | 0.8 (0.2-11) | 0.6 (0.05-40) | 0.6 (0.05-40) |
| Hematocrit (%) | 26 (17-35) | 26 (14-32) | 24 (20-33) | 25 (14-33) |
| Posttransfusion absolute platelet count increment (× 109/L) | ||||
| Early (1-4 h) | 19 (−12-66) | 41 (5-133) | 82 (−4-188) | 61 (−4-188) |
| Late (18-24 h) | 8 (−9-50) | 25 (−1-74) | 52 (−4-137) | 41 (−4-137) |
| Posttransfusion platelet count (× 109/L) | ||||
| Maximum | 32 (4-216) | 52 (16-143) | 93 (2-192) | 77 (2-192) |
| Early (1-4 h) | 31 (3-76) | 52 (14-143) | 92 (2-192) | 74 (2-192) |
| More than 50 × 109/L (%)3-150 | 18 | 56 | 77 | 72 |
| More than 75 × 109/L (%)3-150 | 1 | 11 | 60 | 49 |
| Late (18-24 h) | 22 (4-66) | 35 (10-84) | 66 (1-148) | 52 (1-148) |
Ranges appear in parentheses.
WBC indicates white blood cell count.
Transfusion percentages when posttransfusion platelet counts exceeded indicated values.