Follow-up cytogenetic studies among patients with improved cytogenetic response on PEG IFN-α-2b
| Patient . | Percent Ph+ metaphases on PEG IFN-α-2b therapy . | ||||||
|---|---|---|---|---|---|---|---|
| Pretreatment . | Best (overall) . | At 3 months . | At 6 months . | At 9 months . | At 12 months . | After 12 months [month of therapy] . | |
| 9 | 100 | 0 | — | 95 | 95 | 100 | 65 [18], 40 [26], 0 [30] |
| 13 | 15 | 0 | 10 | 10 | 0 | 15 | 0 [14], 30 [17], 10 [20], 65 [24], 25 [26] |
| 14 | 100 | 0 | 100 | 95 | 95 | 75 | 55 [15], 0 [25] |
| 15 | 50 | 0 | 60 | 40 | 30 | 13 | 0 [16], 25 [25] |
| 17 | 50 | 0 | 0 | 0 | 0 | 0 | 0 [16], 0 [24] |
| 20 | 30 | 5 | 14 | 5 | 35 | Insufficient | 10 [13], 30 [17], 45 [24] |
| 23 | 20 | 0 | 15 | 0 | 0 | 0 | 5 [19] |
| 25 | 69 | 17 (1 mo) | 90 | 90 | 100 | — | — |
| 27 | 75 | 25 | 75 | 47 | 25 | — | 25 [21] |
| Patient . | Percent Ph+ metaphases on PEG IFN-α-2b therapy . | ||||||
|---|---|---|---|---|---|---|---|
| Pretreatment . | Best (overall) . | At 3 months . | At 6 months . | At 9 months . | At 12 months . | After 12 months [month of therapy] . | |
| 9 | 100 | 0 | — | 95 | 95 | 100 | 65 [18], 40 [26], 0 [30] |
| 13 | 15 | 0 | 10 | 10 | 0 | 15 | 0 [14], 30 [17], 10 [20], 65 [24], 25 [26] |
| 14 | 100 | 0 | 100 | 95 | 95 | 75 | 55 [15], 0 [25] |
| 15 | 50 | 0 | 60 | 40 | 30 | 13 | 0 [16], 25 [25] |
| 17 | 50 | 0 | 0 | 0 | 0 | 0 | 0 [16], 0 [24] |
| 20 | 30 | 5 | 14 | 5 | 35 | Insufficient | 10 [13], 30 [17], 45 [24] |
| 23 | 20 | 0 | 15 | 0 | 0 | 0 | 5 [19] |
| 25 | 69 | 17 (1 mo) | 90 | 90 | 100 | — | — |
| 27 | 75 | 25 | 75 | 47 | 25 | — | 25 [21] |