Toxicity grade 3 and 4 according to NCI category (n = 29)
| . | No. of patients . | |
|---|---|---|
| Grade 3 . | Grade 4 . | |
| Blood/bone marrow | ||
| Hemoglobin | 1 | 0 |
| Cardiovascular | ||
| Hypertension | 2 | 0 |
| Hypotension | 1 | 0 |
| Flulike symptoms (fever, rigors/chills) | 4 | 0 |
| Hepatic | ||
| Alkaline phosphatase | 1 | 0 |
| Other | 1 | 0 |
| Infection | 3 | 2 |
| Osseous (bone pain) | 1 | 0 |
| Pulmonary | ||
| Shortness of breath | 1 | 0 |
| Other | 1 | 0 |
| Skin | 1 | 15-150 |
| 17 | 3 | |
| . | No. of patients . | |
|---|---|---|
| Grade 3 . | Grade 4 . | |
| Blood/bone marrow | ||
| Hemoglobin | 1 | 0 |
| Cardiovascular | ||
| Hypertension | 2 | 0 |
| Hypotension | 1 | 0 |
| Flulike symptoms (fever, rigors/chills) | 4 | 0 |
| Hepatic | ||
| Alkaline phosphatase | 1 | 0 |
| Other | 1 | 0 |
| Infection | 3 | 2 |
| Osseous (bone pain) | 1 | 0 |
| Pulmonary | ||
| Shortness of breath | 1 | 0 |
| Other | 1 | 0 |
| Skin | 1 | 15-150 |
| 17 | 3 | |
Generalized herpes zoster infection.