Association of genotype with severe acute GVHD
| Genotype . | t test . | P . |
|---|---|---|
| RIFNγIntron1-3/3 | +2.09 | .046 |
| RIFNγIntron1-3+ | +0.76 | .452 |
| RIFNγIntron1-2/2 | −0.40 | .692 |
| RIFNγIntron1-2+ | −1.84 | .073 |
| RIL-6−174GG | +0.71 | .480 |
| RIL-6−174G+ | +1.59 | .125 |
| RIL-10−1064i(12-16)+ | +2.53 | .014 |
| RTNFd3d3 | +1.94 | .059 |
| DIFNγIntron1-3/3 | −0.34 | .736 |
| DIFNγIntron1-3+ | −0.36 | .717 |
| DIFNγIntron1-2/2 | +0.25 | .804 |
| DIFNγIntron1-2+ | +0.38 | .703 |
| DIL-6−174GG | −0.31 | .761 |
| DIL-6−174G+ | +0.91 | .928 |
| Genotype . | t test . | P . |
|---|---|---|
| RIFNγIntron1-3/3 | +2.09 | .046 |
| RIFNγIntron1-3+ | +0.76 | .452 |
| RIFNγIntron1-2/2 | −0.40 | .692 |
| RIFNγIntron1-2+ | −1.84 | .073 |
| RIL-6−174GG | +0.71 | .480 |
| RIL-6−174G+ | +1.59 | .125 |
| RIL-10−1064i(12-16)+ | +2.53 | .014 |
| RTNFd3d3 | +1.94 | .059 |
| DIFNγIntron1-3/3 | −0.34 | .736 |
| DIFNγIntron1-3+ | −0.36 | .717 |
| DIFNγIntron1-2/2 | +0.25 | .804 |
| DIFNγIntron1-2+ | +0.38 | .703 |
| DIL-6−174GG | −0.31 | .761 |
| DIL-6−174G+ | +0.91 | .928 |
Univariable analysis of association of genotype with severe aGVHD (grades III-IV) versus nonsevere (0-II) by Kruskal-Wallis test. Recipient IFNγIntron1, IL-10−1064, and TNFd genotype associate with severe (grades III-IV) aGVHD.
R indicates recipient; D, donor.