Table 1.

Prevalence of engraftment of maternal T cells in different severe combined immunodeficiency variants

Patients (no.)Maternal T-cell engraftment
(no.)(%)
Reticular dysgenesis 100  
B SCID 26 16 62 
B+ SCID 52 26 50  
ADA/PNP deficiency 10 0  
MHC class II deficiency 10 
Omenn syndrome 0  
Absent CD8+ T cells 0  
Other T+ SCID 
All patients 121 48 40 
Patients (no.)Maternal T-cell engraftment
(no.)(%)
Reticular dysgenesis 100  
B SCID 26 16 62 
B+ SCID 52 26 50  
ADA/PNP deficiency 10 0  
MHC class II deficiency 10 
Omenn syndrome 0  
Absent CD8+ T cells 0  
Other T+ SCID 
All patients 121 48 40 

SCID indicates severe combined immunodeficiency; ADA, adenosine deaminase; PNP, purine nucleoside phosphorylase; MHC, major histocompatibility complex.

Close Modal

or Create an Account

Close Modal
Close Modal