Table 3. Comparison of the number of... | American Society of Hematology

Table 3.

Comparison of the number of lymphocytes between the ALPS Ia family groups and between the proband Ia group and the proband II/III group

Lymphocyte subset	Proband Ia vs M⁺/A⁺	Proband Ia vs M⁺/A⁻	Proband Ia vs M⁻/A⁻	M⁺/A⁺ vs M⁺/A⁻	M⁺/A⁺ vs M⁻/A⁻	M⁺/A⁻ vs M⁻/A⁻	Proband Ia vs proband II/III
T cells
CD3⁺	NS	P= .001↑	P = .006↑	P = .003↑	NS	P = .06↓	NS
CD4⁺	NS	NS	NS	NS	NS	P= .005↓	NS
CD8⁺	NS	P = .001↑	P = .003↑	P = .04↑	NS	NS	NS
α/β⁺-DNT	NS	P < .0001↑	P < .0001↑	P < .0001↑	P < .0001↑	NS	NS
γ/δ⁺-DNT	P = .01↑	P < .0001↑	P < .0001↑	NS	NS	NS	NS
CD3⁺/HLA-DR⁺	NS	P < .0001↑	P < .0001↑	P < .0001↑	P < .0001↑	NS	NS
CD3⁺/CD25⁺	NS	P = .01↓	P = .002↓	NS	NS	NS	NS
CD8⁺/CD57⁺	NS	P = .004↑	P = .01↑	P = .004↑	P = .04↑	NS	NS
B cells
CD20⁺	P = .01↑	P = .009↑	P < .0001↑	P = .003↑	NS	P = .01↓	NS
CD5⁺/CD20⁺	P = .003↑	P < .0001↑	P < .0001↑	P = .006↑	NS	P = .007↓	NS
NK cells
CD3⁻CD16⁺and/or 56⁺	NS	NS	NS	NS	NS	NS	NS

Lymphocyte subset	Proband Ia vs M⁺/A⁺	Proband Ia vs M⁺/A⁻	Proband Ia vs M⁻/A⁻	M⁺/A⁺ vs M⁺/A⁻	M⁺/A⁺ vs M⁻/A⁻	M⁺/A⁻ vs M⁻/A⁻	Proband Ia vs proband II/III
T cells
CD3⁺	NS	P= .001↑	P = .006↑	P = .003↑	NS	P = .06↓	NS
CD4⁺	NS	NS	NS	NS	NS	P= .005↓	NS
CD8⁺	NS	P = .001↑	P = .003↑	P = .04↑	NS	NS	NS
α/β⁺-DNT	NS	P < .0001↑	P < .0001↑	P < .0001↑	P < .0001↑	NS	NS
γ/δ⁺-DNT	P = .01↑	P < .0001↑	P < .0001↑	NS	NS	NS	NS
CD3⁺/HLA-DR⁺	NS	P < .0001↑	P < .0001↑	P < .0001↑	P < .0001↑	NS	NS
CD3⁺/CD25⁺	NS	P = .01↓	P = .002↓	NS	NS	NS	NS
CD8⁺/CD57⁺	NS	P = .004↑	P = .01↑	P = .004↑	P = .04↑	NS	NS
B cells
CD20⁺	P = .01↑	P = .009↑	P < .0001↑	P = .003↑	NS	P = .01↓	NS
CD5⁺/CD20⁺	P = .003↑	P < .0001↑	P < .0001↑	P = .006↑	NS	P = .007↓	NS
NK cells
CD3⁻CD16⁺and/or 56⁺	NS	NS	NS	NS	NS	NS	NS

NS indicates not significant.

↑Absolute number first group higher than second group.

↓Absolute number first group lower than second group.