Multilineage reconstitution potential of different murine hematopoietic cell types
| Cells transplanted . | Percent donor (no. mice) . | Percent donor cells among B cells . | Percent donor cells among T cells . | Percent donor cells among myeloid cells . | CFC/femur . |
|---|---|---|---|---|---|
| 2 × 106BM | 76 ± 1 (11) | 98 ± 1 | 34 ± 2 | 85 ± 2 | 66 700 ± 9 030 |
| 2 × 106FL | 96 ± 1 (12) | 100 ± 0 | 84 ± 1 | 94 ± 1 | 66 160 ± 6 340 |
| 2 × 106MPB | 70 ± 7 (21) | 80 ± 7 | 57 ± 5 | 61 ± 9 | 33 840 ± 2 670 |
| CFC normalized FL | 94 ± 1 (19) | 98 ± 1 | 57 ± 4 | 96 ± 1 | 62 670 ± 4 230 |
| CFC normalized MPB | 67 ± 5 (28) | 75 ± 5 | 49 ± 5 | 53 ± 7 | 40 810 ± 3 320 |
| Cells transplanted . | Percent donor (no. mice) . | Percent donor cells among B cells . | Percent donor cells among T cells . | Percent donor cells among myeloid cells . | CFC/femur . |
|---|---|---|---|---|---|
| 2 × 106BM | 76 ± 1 (11) | 98 ± 1 | 34 ± 2 | 85 ± 2 | 66 700 ± 9 030 |
| 2 × 106FL | 96 ± 1 (12) | 100 ± 0 | 84 ± 1 | 94 ± 1 | 66 160 ± 6 340 |
| 2 × 106MPB | 70 ± 7 (21) | 80 ± 7 | 57 ± 5 | 61 ± 9 | 33 840 ± 2 670 |
| CFC normalized FL | 94 ± 1 (19) | 98 ± 1 | 57 ± 4 | 96 ± 1 | 62 670 ± 4 230 |
| CFC normalized MPB | 67 ± 5 (28) | 75 ± 5 | 49 ± 5 | 53 ± 7 | 40 810 ± 3 320 |
Lethally irradiated Ly-5.1 mice received transplants with the indicated cells (Ly-5.2+). Four months later, the percent of donor-derived cells in various lineages of peripheral blood cells was determined by flow cytometry. Hematopoietic progenitors in the BM were assayed by plating in semisolid medium. All values are expressed as the mean ± SEM.