Table 6.

Relapse and leukemia-free survival rates after allogeneic PBSCT or BMT

StudyRelapse rateDisease-free survival rate (overall survival rate)
BM (%)PBSC (%)BM (%)PBSC (%)
Vigorito et al38 10.5 (median FU, 631 d) 11 (median FU, 335 d) 52 (at 1000 d) 58 (at 1000 d)  
Blaise et al39 9 (median FU, 20 mo) 9 (median FU, 20 mo) 66 (at 2 y) 67 (at 2 y)  
Ringden et al40 38 (1-y probability) 34 (1-y probability) 48 overall 46 overall 
   70 (low risk) 63 (low risk)  
   33 (high risk) 31 (high risk)  
   (at 1 y) (at 1 y)  
Heldal et al41 30 (median FU, 36 mo) 3.2 (median FU, 34 mo) NA NA  
Powles et al42 376-150 (2-y probability) 06-150 (2-y probability) NA NA  
Schmitz et al43 No significant difference No significant difference No significant difference No significant difference 
Simpson et al44 NA NA (55 [at 2 y])6-150 (68 [at 2 y])6-150 
Champlin et al45 11 AL CR1 14 AL CR1 61 AL CR1 70 AL CR1 
 13 AL CR2 8 AL CR2 57 AL CR26-150 77 AL CR26-150 
 1 CML CP1 2 CML CP1 74 CML CP1 63 CML CP1  
 21 CML AP 13 CML AP 23 CML AP6-150 68 CML AP6-150 
 (1-y probability) (1-y probability) (1-y probability) (1-y probability)  
Bensinger et al10 25 (at 2 y) 14 (at 2 y) 45 overall6-150 65 overall6-150 
   72 (less advanced cancer) 75 (less advanced cancer) 
   336-150 (more advanced cancer) 576-150(more advanced cancer)  
   (at 2 y) (at 2 y) 
   (54 [at 2 y])6-150 (66 [at 2 y])6-150 
StudyRelapse rateDisease-free survival rate (overall survival rate)
BM (%)PBSC (%)BM (%)PBSC (%)
Vigorito et al38 10.5 (median FU, 631 d) 11 (median FU, 335 d) 52 (at 1000 d) 58 (at 1000 d)  
Blaise et al39 9 (median FU, 20 mo) 9 (median FU, 20 mo) 66 (at 2 y) 67 (at 2 y)  
Ringden et al40 38 (1-y probability) 34 (1-y probability) 48 overall 46 overall 
   70 (low risk) 63 (low risk)  
   33 (high risk) 31 (high risk)  
   (at 1 y) (at 1 y)  
Heldal et al41 30 (median FU, 36 mo) 3.2 (median FU, 34 mo) NA NA  
Powles et al42 376-150 (2-y probability) 06-150 (2-y probability) NA NA  
Schmitz et al43 No significant difference No significant difference No significant difference No significant difference 
Simpson et al44 NA NA (55 [at 2 y])6-150 (68 [at 2 y])6-150 
Champlin et al45 11 AL CR1 14 AL CR1 61 AL CR1 70 AL CR1 
 13 AL CR2 8 AL CR2 57 AL CR26-150 77 AL CR26-150 
 1 CML CP1 2 CML CP1 74 CML CP1 63 CML CP1  
 21 CML AP 13 CML AP 23 CML AP6-150 68 CML AP6-150 
 (1-y probability) (1-y probability) (1-y probability) (1-y probability)  
Bensinger et al10 25 (at 2 y) 14 (at 2 y) 45 overall6-150 65 overall6-150 
   72 (less advanced cancer) 75 (less advanced cancer) 
   336-150 (more advanced cancer) 576-150(more advanced cancer)  
   (at 2 y) (at 2 y) 
   (54 [at 2 y])6-150 (66 [at 2 y])6-150 

Abbreviations are explained in Tables 4 and 5.

F6-150

Statistical significance.

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