Clonal deletion of donor-reactive host T cells in B10.BR B10 chimeras
| . | % of CD4+ T cells (SEM) expressing . | % of CD8+ T cells (SEM) expressing . | ||||
|---|---|---|---|---|---|---|
| Vβ5 . | Vβ11 . | Vβ8 . | Vβ5 . | Vβ11 . | Vβ8 . | |
| Strain (n) | ||||||
| B10 (3) | 1.54 (.08) | 5.00 (.31) | 17.44 (1.08) | 11.06 (.67) | 6.84 (.61) | 16.79 (1.6) |
| B10.BR (3) | 0.17 (.17) | 0.17 (.03) | 15.36 (.52) | 1.59 (.63) | 1.54 (.42) | 19.82 (4.4) |
| B10.BR → B10* (4) | 0.43 (.16) | 0.30 (.05) | 18.69 (.69) | 0.94 (.23) | 1.58 (.12) | 20.78 (1.1) |
| Comparison, P | ||||||
| B10.BR → B10 vs B10 | .0026 | .00002 | .35 | .0005 | .0007 | .60 |
| B10.BR → B10 vs B10.BR | .31 | .09 | 0.02 | .38 | .94 | .86 |
| . | % of CD4+ T cells (SEM) expressing . | % of CD8+ T cells (SEM) expressing . | ||||
|---|---|---|---|---|---|---|
| Vβ5 . | Vβ11 . | Vβ8 . | Vβ5 . | Vβ11 . | Vβ8 . | |
| Strain (n) | ||||||
| B10 (3) | 1.54 (.08) | 5.00 (.31) | 17.44 (1.08) | 11.06 (.67) | 6.84 (.61) | 16.79 (1.6) |
| B10.BR (3) | 0.17 (.17) | 0.17 (.03) | 15.36 (.52) | 1.59 (.63) | 1.54 (.42) | 19.82 (4.4) |
| B10.BR → B10* (4) | 0.43 (.16) | 0.30 (.05) | 18.69 (.69) | 0.94 (.23) | 1.58 (.12) | 20.78 (1.1) |
| Comparison, P | ||||||
| B10.BR → B10 vs B10 | .0026 | .00002 | .35 | .0005 | .0007 | .60 |
| B10.BR → B10 vs B10.BR | .31 | .09 | 0.02 | .38 | .94 | .86 |
Numbers in this row indicate the percentage of host (B10)–derived T cells that express the indicated Vβ gene product. Mean (±SEM) peripheral blood donor chimerism in these animals was 14.46% ± 4.53%.