Table 3.

Characteristics of validation cohort: patients from 5 medical centers who required mechanical ventilation within one year of hematopoietic stem cell transplantation (n = 226)

CharacteristicMean (SD) or N (%)
Demographics  
 Age (y) 43 ± 11  
 Male 129  (57) 
 Female 97  (43)  
 Time from hematopoietic stem cell transplantation to mechanical ventilation (median/range) 27/(0-365)  
Details of hematopoietic stem cell transplantation  
 Allogeneic transplant  
  Matched3-150 121  (54) 
  Unmatched3-151 39  (17)  
 Autologous transplant 66  (29)  
Source of stem cells  
 Peripheral blood 33  (15)  
 Bone marrow 193  (85)  
Indication for hematopoietic stem cell transplantation  
 Leukemia 122  (54) 
 Lymphoma 43  (19)  
 Other hematologic disorder3-152 34  (15)  
 Solid tumor 27  (12) 
Study center  
 Memorial Sloan-Kettering Cancer Center, New York, NY 75  (33)  
 City of Hope Cancer Center, Duarte, CA 66  (29)  
 University of Texas M. D. Anderson Cancer Center, Houston, TX 46  (20)  
 Johns Hopkins Oncology Center, Baltimore, MD 30  (13)  
 Mount Sinai Medical Center, New York, NY 9  (4) 
CharacteristicMean (SD) or N (%)
Demographics  
 Age (y) 43 ± 11  
 Male 129  (57) 
 Female 97  (43)  
 Time from hematopoietic stem cell transplantation to mechanical ventilation (median/range) 27/(0-365)  
Details of hematopoietic stem cell transplantation  
 Allogeneic transplant  
  Matched3-150 121  (54) 
  Unmatched3-151 39  (17)  
 Autologous transplant 66  (29)  
Source of stem cells  
 Peripheral blood 33  (15)  
 Bone marrow 193  (85)  
Indication for hematopoietic stem cell transplantation  
 Leukemia 122  (54) 
 Lymphoma 43  (19)  
 Other hematologic disorder3-152 34  (15)  
 Solid tumor 27  (12) 
Study center  
 Memorial Sloan-Kettering Cancer Center, New York, NY 75  (33)  
 City of Hope Cancer Center, Duarte, CA 66  (29)  
 University of Texas M. D. Anderson Cancer Center, Houston, TX 46  (20)  
 Johns Hopkins Oncology Center, Baltimore, MD 30  (13)  
 Mount Sinai Medical Center, New York, NY 9  (4) 
F3-150

Donor and recipient related and/or major human leukocyte antigens (HLA) identical.

F3-151

Donor and recipient unrelated and/or HLA major antigen mismatch.

F3-152

Includes multiple myeloma, aplastic anemia, and myelodysplastic syndrome.

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