Table 2.

Primary end point, all recorded coronary ischemic events, myocardial infarction, and bleeding events according to PlAgenotype, showing the number of events by genotype and percent of genotype that had events, according to the treatment groups

EventPlacebo (n = 353)Orbofiban 50/30 mg (n = 353)Orbofiban 50/50 mg (n = 308)
Primary endpoint    
 PlA2 carriers (%) 15  (15.5) 24  (24.0) 11  (15.7) 
 PlA2 noncarriers (%) 48  (18.8) 35  (13.8) 32  (13.5)  
Myocardial infarction    
 PlA2 carriers (%) 3  (3.1) 10  (10.0) 3  (4.3)  
 PlA2 noncarriers (%) 8  (3.1) 4  (1.6) 5  (2.1) 
Bleeding    
 PlA2 carriers (%) 15  (15.5) 16  (16.0) 9  (12.9)  
 PlA2 noncarriers (%) 34  (13.3) 48  (19.0) 65  (27.3) 
EventPlacebo (n = 353)Orbofiban 50/30 mg (n = 353)Orbofiban 50/50 mg (n = 308)
Primary endpoint    
 PlA2 carriers (%) 15  (15.5) 24  (24.0) 11  (15.7) 
 PlA2 noncarriers (%) 48  (18.8) 35  (13.8) 32  (13.5)  
Myocardial infarction    
 PlA2 carriers (%) 3  (3.1) 10  (10.0) 3  (4.3)  
 PlA2 noncarriers (%) 8  (3.1) 4  (1.6) 5  (2.1) 
Bleeding    
 PlA2 carriers (%) 15  (15.5) 16  (16.0) 9  (12.9)  
 PlA2 noncarriers (%) 34  (13.3) 48  (19.0) 65  (27.3) 

Carrier is PlA2/A2 or PlA1/A2 and PlA2 noncarrier is PlA1/A1.

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