Characteristics of patients with congenital afibrinogenemia
| Patient characteristics and treatment . | B1 . | C9 . | F5 . | I3 . | P4 . | R3 . | S2 . | S3 . |
|---|---|---|---|---|---|---|---|---|
| Patient characteristics | ||||||||
| Origin | Barbados | Cagliari | Florence | Iran | Palermo | Rome | Sassari | Sassari |
| Sex | M | M | M | M | F | M | M | M |
| Present age, y | Adult | 36 | 43 | 6 | 4 | 28 | 37 | 41 |
| Main symptoms | Hemarthroses | Posttraumatic hematomas | Mouth and neck bleeding | Hemoperitonem | Asymptomatic | Posttraumatic hematomas | Intracranial hemorrhage | Posttraumatic hematomas |
| Treatment | a | a, b, c | a | b, c | None | a | a | None |
| Plasma fibrinogen levels | ||||||||
| Functional (mg/dL) | < 5 | < 5 | < 5 | < 5 | < 5 | < 5 | < 5 | < 5 |
| Immunologic (mg/dL) | 0.041 | 1.73 | 0.037 | 4.25 | 0.015 | 1.43 | 1.2 | 0.72 |
| Patient characteristics and treatment . | B1 . | C9 . | F5 . | I3 . | P4 . | R3 . | S2 . | S3 . |
|---|---|---|---|---|---|---|---|---|
| Patient characteristics | ||||||||
| Origin | Barbados | Cagliari | Florence | Iran | Palermo | Rome | Sassari | Sassari |
| Sex | M | M | M | M | F | M | M | M |
| Present age, y | Adult | 36 | 43 | 6 | 4 | 28 | 37 | 41 |
| Main symptoms | Hemarthroses | Posttraumatic hematomas | Mouth and neck bleeding | Hemoperitonem | Asymptomatic | Posttraumatic hematomas | Intracranial hemorrhage | Posttraumatic hematomas |
| Treatment | a | a, b, c | a | b, c | None | a | a | None |
| Plasma fibrinogen levels | ||||||||
| Functional (mg/dL) | < 5 | < 5 | < 5 | < 5 | < 5 | < 5 | < 5 | < 5 |
| Immunologic (mg/dL) | 0.041 | 1.73 | 0.037 | 4.25 | 0.015 | 1.43 | 1.2 | 0.72 |
a indicates fibrinogen concentrates; b, whole blood; and c, plasma.