Demographic and clinical characteristics of the study cohort
| . | Severe sepsis/ septic shock . |
|---|---|
| Demographic characteristics | |
| Age, mean ± SD, y | 58.4 ± 16.1 |
| Sex, % female/male | 43/57 |
| Severity of the underlying disease, No. (McCabe/Jackson classification) | |
| Nonfatal | 48 |
| Fatal | 12 |
| Rapidly fatal | 3 |
| APACHE III score, mean ± SD, points | |
| Intensive care unit admission | 61 ± 20 |
| Severe sepsis/septic shock onset | 67 ± 21 |
| SOFA score, mean ± SD, points | |
| Severe sepsis onset/septic shock | 12 ± 4 |
| Length of treatment, median (range), d | |
| Intensive care unit | 14 (1-71) |
| Hospital | 28 (3-148) |
| Mortality, % | |
| Severe sepsis-related | 63.5 |
| Severe sepsis-related less than 3 d | 19.0 |
| All cause 28 d | 63.5 |
| All cause intensive care unit | 65.0 |
| All cause hospital | 69.8 |
| Positive microbial culture, local/blood, % | 55.6/23.8 |
| Gram-positive, No. | 12/6 |
| Gram-negative, No. | 7/4 |
| Polymicrobial, No. | 16/5 |
| Sites of infection, No. | |
| Diffuse peritonitis | 39 |
| Pneumonia | 8 |
| Soft tissue infection | 6 |
| Catheter-associated bloodstream infection | 1 |
| Urogenital infection | 2 |
| Others | 7 |
| . | Severe sepsis/ septic shock . |
|---|---|
| Demographic characteristics | |
| Age, mean ± SD, y | 58.4 ± 16.1 |
| Sex, % female/male | 43/57 |
| Severity of the underlying disease, No. (McCabe/Jackson classification) | |
| Nonfatal | 48 |
| Fatal | 12 |
| Rapidly fatal | 3 |
| APACHE III score, mean ± SD, points | |
| Intensive care unit admission | 61 ± 20 |
| Severe sepsis/septic shock onset | 67 ± 21 |
| SOFA score, mean ± SD, points | |
| Severe sepsis onset/septic shock | 12 ± 4 |
| Length of treatment, median (range), d | |
| Intensive care unit | 14 (1-71) |
| Hospital | 28 (3-148) |
| Mortality, % | |
| Severe sepsis-related | 63.5 |
| Severe sepsis-related less than 3 d | 19.0 |
| All cause 28 d | 63.5 |
| All cause intensive care unit | 65.0 |
| All cause hospital | 69.8 |
| Positive microbial culture, local/blood, % | 55.6/23.8 |
| Gram-positive, No. | 12/6 |
| Gram-negative, No. | 7/4 |
| Polymicrobial, No. | 16/5 |
| Sites of infection, No. | |
| Diffuse peritonitis | 39 |
| Pneumonia | 8 |
| Soft tissue infection | 6 |
| Catheter-associated bloodstream infection | 1 |
| Urogenital infection | 2 |
| Others | 7 |