Table 1.

Northern blot analysis of JAM-1, JAM-2, and JAM-3 expression in murine tissues

TissueJAM-1JAM-2JAM-3
Embryo    
 E7 − ± 
 E11 − ±  
 E15 − ++ ± 
 E17 − 
Adult    
 Heart +++ ++ 
 Lungs +++ ± ±  
 Liver +++ ± ± 
 Spleen ± − −  
 Kidney ++ ++ ± 
 Testis +++ +++  
 Thymus ++ ± 
 Peyer patches ++ ++ +  
 Lymph nodes ++ ++ 
TissueJAM-1JAM-2JAM-3
Embryo    
 E7 − ± 
 E11 − ±  
 E15 − ++ ± 
 E17 − 
Adult    
 Heart +++ ++ 
 Lungs +++ ± ±  
 Liver +++ ± ± 
 Spleen ± − −  
 Kidney ++ ++ ± 
 Testis +++ +++  
 Thymus ++ ± 
 Peyer patches ++ ++ +  
 Lymph nodes ++ ++ 

− indicates absence of detectable signal; ±, +, ++, +++, gradual increases in hybridization signals. Results were normalized to the β-actin hybridization signal and represent relative intensities of the hybridization signal (see Figure 2A).

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