Table 2. Summary of histologic features,... | American Society of Hematology

Table 2.

Summary of histologic features, immunophenotype, and molecular analysis of AITL cases

Case no.	Pattern^*	CD10/ CD3^†(%)	Clear cells^‡	CD10/ Ki67^2-153(%)	TCR PCR	IgH PCR
1	I	5	Absent		O	P
2	I	5	Absent	16	M	P
3	I	10	Present		O	P
4	I	10	Absent		M	P
5	I	20	Present	8	M	P
6	I	0	Absent		M	P
7	II	5	Absent		P	P
8	II	5	Absent		M	P
9	II	5	Absent	11	M	P
10	II	10	Present	19	O	P
11	II	10	Present		M	M
12	II	15	Present		M	P
13	II	20	Absent		M	M
14	II	20	Absent		O	M
15A	II	5	Absent		M	P
15B	III	5	Present		M	P
16A	II	0	Absent		M	P
16B	III	0	Absent		M	M
17	III	5	Present		M	P
18	III	5	Present		M	P
19	III	5	Present		M	P
20	III	5	Present		O	M
21	III	10	Absent		M	P
22	III	10	Absent		M	P
23	III	20	Present		M	P
24	III	20	Present		M	NA
25	III	20	Present	10	M	P
26	III	30	Absent	11	O	P
27	III	30	Present	19	M	M
28	III	30	Present		M	P
29	III	30	Present		O	P
30	III	0	Present		M	P

Case no.	Pattern^*	CD10/ CD3^†(%)	Clear cells^‡	CD10/ Ki67^2-153(%)	TCR PCR	IgH PCR
1	I	5	Absent		O	P
2	I	5	Absent	16	M	P
3	I	10	Present		O	P
4	I	10	Absent		M	P
5	I	20	Present	8	M	P
6	I	0	Absent		M	P
7	II	5	Absent		P	P
8	II	5	Absent		M	P
9	II	5	Absent	11	M	P
10	II	10	Present	19	O	P
11	II	10	Present		M	M
12	II	15	Present		M	P
13	II	20	Absent		M	M
14	II	20	Absent		O	M
15A	II	5	Absent		M	P
15B	III	5	Present		M	P
16A	II	0	Absent		M	P
16B	III	0	Absent		M	M
17	III	5	Present		M	P
18	III	5	Present		M	P
19	III	5	Present		M	P
20	III	5	Present		O	M
21	III	10	Absent		M	P
22	III	10	Absent		M	P
23	III	20	Present		M	P
24	III	20	Present		M	NA
25	III	20	Present	10	M	P
26	III	30	Absent	11	O	P
27	III	30	Present	19	M	M
28	III	30	Present		M	P
29	III	30	Present		O	P
30	III	0	Present		M	P

TCR indicates T-cell receptor-γ chain gene; PCR, polymerase chain reaction; IgH, immunoglobulin heavy chain gene; M, monoclonal; O, oligoclonal; P, polyclonal; NA, no amplification.

The histologic pattern as described in “Results.”

†

Percentage of CD10⁺ and CD3⁺ T cells.

‡

Cases containing aggregates of atypical lymphoid cells with clear cytoplasm.

F2-153

Percentage of CD10⁺ cells expressing Ki67.

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