Doses used to treat bleeding episodes by subtype of von Willebrand disease
| . | VWD subtype . | ||
|---|---|---|---|
| Type 1 . | Type 2A . | Type 3 . | |
| No. patients | 3 | 7 | 4 |
| No. bleeding episodes | 4 | 67 | 16 |
| Total no. infusions | 5 | 86 | 44 |
| Median no. infusions per bleeding episode (range) | 1.0 (1-2) | 1.0 (1-7) | 3.0 (1-6) |
| Median VWF:RCof dosage per infusion, IU/kg | |||
| 1 infusion (range) | 45 (33-56) | 40 (14-50) | 40 (14-79) |
| 2 or more infusions (range) | 55 (55-55) | 40 (14-50) | 60 (19-79) |
| All infusions (range) | 50 (33-56) | 40 (14-50) | 60 (14-79) |
| Median treatment interval, h (range) | 24 (24-24) | 24 (20-71) | 16 (7-69) |
| . | VWD subtype . | ||
|---|---|---|---|
| Type 1 . | Type 2A . | Type 3 . | |
| No. patients | 3 | 7 | 4 |
| No. bleeding episodes | 4 | 67 | 16 |
| Total no. infusions | 5 | 86 | 44 |
| Median no. infusions per bleeding episode (range) | 1.0 (1-2) | 1.0 (1-7) | 3.0 (1-6) |
| Median VWF:RCof dosage per infusion, IU/kg | |||
| 1 infusion (range) | 45 (33-56) | 40 (14-50) | 40 (14-79) |
| 2 or more infusions (range) | 55 (55-55) | 40 (14-50) | 60 (19-79) |
| All infusions (range) | 50 (33-56) | 40 (14-50) | 60 (14-79) |
| Median treatment interval, h (range) | 24 (24-24) | 24 (20-71) | 16 (7-69) |
Median treatment interval was measured from preceding infusion, across all infusions.