Induction of proliferation by SDF-1 and IL-10
| SDF-1 . | IL-10 . | Peritoneal cell subpopulations . | ||
|---|---|---|---|---|
| B1a . | B1b . | B2 . | ||
| − | − | 2.1 ± 0.4 | 3.1 ± 0.5 | 2.2 ± 0.2 |
| + | − | 10.7 ± 1.9* | 13.6 ± 2.1* | 9.2 ± 1.5* |
| − | + | 5.5 ± 0.5* | 7.6 ± 1.5* | 4.8 ± 0.5* |
| + | + | 25.8 ± 4.2*,† | 30.1 ± 4.5*,† | 21.2 ± 3.5*,† |
| SDF-1 . | IL-10 . | Peritoneal cell subpopulations . | ||
|---|---|---|---|---|
| B1a . | B1b . | B2 . | ||
| − | − | 2.1 ± 0.4 | 3.1 ± 0.5 | 2.2 ± 0.2 |
| + | − | 10.7 ± 1.9* | 13.6 ± 2.1* | 9.2 ± 1.5* |
| − | + | 5.5 ± 0.5* | 7.6 ± 1.5* | 4.8 ± 0.5* |
| + | + | 25.8 ± 4.2*,† | 30.1 ± 4.5*,† | 21.2 ± 3.5*,† |
Results are from 4 independent 5(6) CFDA, SE assays. They are expressed as the percentage (mean ± SEM) of cells resulting from cell division at the end of culture.
SDF-1 indicates stromal cell-derived factor-1; IL-10, interleukin 10.
P < .05 versus controls.
P < .05 versus SDF-1-induced proliferation.