PVSG diagnostic criteria for PV
| Category A | A1 | Increased red cell mass |
| M ≥ 36 mL/kg | ||
| F ≥ 32 mL/kg | ||
| A2 | Oxygen saturation ≥ 92% | |
| A3 | Splenomegaly | |
| Category B | B1 | Platelets ≥ 400 × 109/L (400 000/μL) |
| B2 | White blood count ≥ 12 × 109/L (12 000/μL)7-150 | |
| B3 | LAP score > 1007-150 | |
| B4 | Serum B12 > 900 pg/mL (660 pM) | |
| U B12 BC > 2200 pg/mL (1620 pM) |
| Category A | A1 | Increased red cell mass |
| M ≥ 36 mL/kg | ||
| F ≥ 32 mL/kg | ||
| A2 | Oxygen saturation ≥ 92% | |
| A3 | Splenomegaly | |
| Category B | B1 | Platelets ≥ 400 × 109/L (400 000/μL) |
| B2 | White blood count ≥ 12 × 109/L (12 000/μL)7-150 | |
| B3 | LAP score > 1007-150 | |
| B4 | Serum B12 > 900 pg/mL (660 pM) | |
| U B12 BC > 2200 pg/mL (1620 pM) |
U B12 BC indicates unbound vitamin B12binding capacity.
In absence of fever or infection.
Adapted from Peterson P, Wasserman LR. The natural history of polycythemia vera. In: Wasserman LR, Berk PD, Berlin NI, eds. Polycythemia Vera and the Myeloproliferative Disorders. Philadelphia, PA: WB Saunders; 1995:14-21.