Comparison of the clinical and immunologic characteristics of the BCR-ABL+ and BCR-ABL− patients
| Characteristics . | BCR-ABL−5-150 n = 257 (%) . | BCR-ABL+5-150 n = 175 (%) . | P . |
|---|---|---|---|
| Age (y) | |||
| 15-20 | 64 (25) | 8 (5) | .0015-151 |
| 20-50 | 141 (55) | 98 (56) | |
| 50-65 | 52 (20) | 69 (39) | |
| Median | 30 (15-64) | 45 (15-65) | .00015-152 |
| WBC (× 109/L)5-153 | |||
| < 30 000 | 185 (72) | 97 (55) | .0015-155 |
| > 30 000 | 71 (28) | 78 (45) | |
| Median | 11 550 (22-720 000) | 23 500 (1500-3 531 000) | .00015-152 |
| Granulocytes (× 109/L) | |||
| Median | 1080 (0-28 400) | 2219 (0-494 340) | .00015-152 |
| Hemoglobin (g/dL) | |||
| Median | 9.2 (2.5-16) | 10.2 (3-16.3) | .0045-152 |
| Immunophenotype | |||
| CD34 > 20% | 169 (66) | 164 (94) | .0015-155 |
| CD13 > 20%5-154 | 36 (14) | 46 (27) | .0015-155 |
| CD33 > 20%5-159 | 45 (18) | 126 (27) | .0015-155 |
| Characteristics . | BCR-ABL−5-150 n = 257 (%) . | BCR-ABL+5-150 n = 175 (%) . | P . |
|---|---|---|---|
| Age (y) | |||
| 15-20 | 64 (25) | 8 (5) | .0015-151 |
| 20-50 | 141 (55) | 98 (56) | |
| 50-65 | 52 (20) | 69 (39) | |
| Median | 30 (15-64) | 45 (15-65) | .00015-152 |
| WBC (× 109/L)5-153 | |||
| < 30 000 | 185 (72) | 97 (55) | .0015-155 |
| > 30 000 | 71 (28) | 78 (45) | |
| Median | 11 550 (22-720 000) | 23 500 (1500-3 531 000) | .00015-152 |
| Granulocytes (× 109/L) | |||
| Median | 1080 (0-28 400) | 2219 (0-494 340) | .00015-152 |
| Hemoglobin (g/dL) | |||
| Median | 9.2 (2.5-16) | 10.2 (3-16.3) | .0045-152 |
| Immunophenotype | |||
| CD34 > 20% | 169 (66) | 164 (94) | .0015-155 |
| CD13 > 20%5-154 | 36 (14) | 46 (27) | .0015-155 |
| CD33 > 20%5-159 | 45 (18) | 126 (27) | .0015-155 |
In each column is given the number (percent) of patients with a certain clinical feature such as age or WBC within the group of all BCR-ABL− or BCR-ABL+ patients. Prefers to the comparison of each clinical parameter in BCR-ABL− versus BCR-ABL+ patients.
c-ALL and pre-B ALL only.
P by Fisher exact text.
P by Wilcoxon 2-sample test.
Data for 1 patient missing.
P by χ2 test.
Data for 5 patients are missing.
Data for 3 patients are missing.