Cytolytic characteristics of EBV-specific CTLs with or without chimeric receptors
CTL line . | % specific lysis* . | Posttransduction day . | ||||||
---|---|---|---|---|---|---|---|---|
Nontransduced . | 14.G2a-ζ transduced . | |||||||
Auto LCL . | Allo LCL . | LAN-1 . | Auto LCL . | Allo LCL . | LAN-1 . | A-204 . | ||
1 | 61 | 23 | 0 | 55 | 19 | 45 | 29 | |
2 | 49 | 5 | 0 | 48 | 5 | 47 | 8 | |
3 | 49 | 11 | 0 | 38 | 5 | 26 | 8 | |
4 | 53 | 12 | 35 | 13 | 50 | 8 | ||
5 | 50 | 5 | 42 | 3 | 21 | 7 | ||
6 | 49 | 22 | 66 | 28 | 22 | |||
7 | 33 | 6 | 30 | 8 | 48 | 0 | 9 | |
8 | 27 | 7 | 52 | 3 | 43 | 5 | 9 | |
9 | 45 | 0 | 5 | 45 | 5 | 32 | 4 | 9 |
10† | 81 | 10 | 1 | 65 | 0 | 26 | 0 | 15 |
CTL line . | % specific lysis* . | Posttransduction day . | ||||||
---|---|---|---|---|---|---|---|---|
Nontransduced . | 14.G2a-ζ transduced . | |||||||
Auto LCL . | Allo LCL . | LAN-1 . | Auto LCL . | Allo LCL . | LAN-1 . | A-204 . | ||
1 | 61 | 23 | 0 | 55 | 19 | 45 | 29 | |
2 | 49 | 5 | 0 | 48 | 5 | 47 | 8 | |
3 | 49 | 11 | 0 | 38 | 5 | 26 | 8 | |
4 | 53 | 12 | 35 | 13 | 50 | 8 | ||
5 | 50 | 5 | 42 | 3 | 21 | 7 | ||
6 | 49 | 22 | 66 | 28 | 22 | |||
7 | 33 | 6 | 30 | 8 | 48 | 0 | 9 | |
8 | 27 | 7 | 52 | 3 | 43 | 5 | 9 | |
9 | 45 | 0 | 5 | 45 | 5 | 32 | 4 | 9 |
10† | 81 | 10 | 1 | 65 | 0 | 26 | 0 | 15 |