Table 1.

Cytolytic characteristics of EBV-specific CTLs with or without chimeric receptors

CTL line% specific lysis*Posttransduction day
Nontransduced14.G2a-ζ transduced
Auto LCLAllo LCLLAN-1Auto LCLAllo LCLLAN-1A-204
61 23 55 19 45  29 
49 48 47  
49 11 38 26  
53 12  35 13 50  
50  42 21  
49 22  66  28  22 
33  30 48 
27  52 43 
45 45 32 
10 81 10 65 26 15 
CTL line% specific lysis*Posttransduction day
Nontransduced14.G2a-ζ transduced
Auto LCLAllo LCLLAN-1Auto LCLAllo LCLLAN-1A-204
61 23 55 19 45  29 
49 48 47  
49 11 38 26  
53 12  35 13 50  
50  42 21  
49 22  66  28  22 
33  30 48 
27  52 43 
45 45 32 
10 81 10 65 26 15 
*

Effector-to-target ratio 40:1.

CTL line 5, retested after additional restimulation with autologous EBV-LCL.

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