Distribution of GVHD scores before therapy with visilizumab
. | Stage or grade . | ||||
---|---|---|---|---|---|
. | 0 . | I . | II . | III . | IV . |
Multidose regimen | |||||
Skin | 4 | 0 | 1 | 1 | 0 |
Liver | 2 | 1 | 0 | 3 | 0 |
Gut | 0 | 0 | 1 | 4 | 1 |
Overall | 0 | 0 | 0 | 5 | 1 |
Single-dose regimen | |||||
Skin | 4 | 0 | 4 | 3 | 0 |
Liver | 7 | 2 | 0 | 2 | 0 |
Gut | 2 | 0 | 0 | 5 | 4 |
Overall | 0 | 0 | 1 | 5 | 5 |
. | Stage or grade . | ||||
---|---|---|---|---|---|
. | 0 . | I . | II . | III . | IV . |
Multidose regimen | |||||
Skin | 4 | 0 | 1 | 1 | 0 |
Liver | 2 | 1 | 0 | 3 | 0 |
Gut | 0 | 0 | 1 | 4 | 1 |
Overall | 0 | 0 | 0 | 5 | 1 |
Single-dose regimen | |||||
Skin | 4 | 0 | 4 | 3 | 0 |
Liver | 7 | 2 | 0 | 2 | 0 |
Gut | 2 | 0 | 0 | 5 | 4 |
Overall | 0 | 0 | 1 | 5 | 5 |
The number of patients with the following symptoms of GVHD included 9 with skin rash, 8 with serum bilirubin level 2.0 mg/dL or higher, 12 with diarrhea, 11 with abdominal cramps, 12 with stool blood, and 13 with nausea or vomiting or both.