Table 2. Age-adjusted OR and 95% CI for... | American Society of Hematology

Table 2.

Age-adjusted OR and 95% CI for VTE in relation to factor V–related variables, LITE

Group (no. of VTE)	Factor V Leiden^*		HR2 Haplotype^*		APC resistant by APC-SR		APC resistant by modified APC-SR		Factor V antigen quintile 5 versus 1
Group (no. of VTE)	OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI
Overall (n = 290-302)	3.67^†	2.20-6.12	1.05	0.64-1.72	1.54^†	1.05-2.25	2.58^†	1.62-4.10	1.60^†	1.03-2.48
Whites only (n = 217-232)	3.69^†	2.18-6.24	1.13	0.68-1.89	1.44	0.93-2.24	2.51^†	1.54-4.09	1.35	0.81-2.23
ARIC (n = 158-170)	4.05^†	2.15-7.64	1.08	0.55-2.12	1.53	0.93-2.52	2.56^†	1.45-4.49	1.41	0.79-2.51
CHS (n = 132-138)	3.16^†	1.31-7.60	0.98	0.47-2.04	1.54	0.86-2.78	2.65^†	1.16-6.09	1.92	0.91-4.04
Incident (n = 253-257)	3.31^†	1.93-5.67	1.05	0.62-1.77	1.33	0.88-2.00	2.28^†	1.39-3.74	1.40	0.88-2.25
Recurrent (n = 37-45)	5.79^†	2.52-13.33	1.07	0.37-3.10	3.33^†	1.60-6.93	4.86^†	2.13-11.08	3.05^†	1.19-7.81
Idiopathic (n = 129-138)	5.91^†	3.34-10.46	1.18	0.62-2.24	1.85^†	1.14-2.99	4.11^†	2.40-7.02	1.97^†	1.09-3.56
Secondary (n = 161-166)	2.02^†	1.01-4.02	0.95	0.50-1.79	1.30	0.80-2.12	1.52	0.81-2.85	1.34	0.77-2.31
DVT (n = 208-216)	3.76^†	2.17-6.53	1.02	0.58-1.78	1.60^†	1.05-2.44	2.63^†	1.58-4.37	1.52	0.94-2.48
PE (n = 44-47)	2.86^†	1.04-7.85	0.79	0.24-2.62	1.03	0.42-2.53	2.21	0.88-5.59	1.24	0.48-3.19
Both (n = 38-42)	4.21^†	1.62-10.93	1.59	0.59-4.23	1.84	0.81-4.17	2.73^†	1.07-6.96	3.68	0.96-14.03

Group (no. of VTE)	Factor V Leiden^*		HR2 Haplotype^*		APC resistant by APC-SR		APC resistant by modified APC-SR		Factor V antigen quintile 5 versus 1
Group (no. of VTE)	OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI	OR	95% CI
Overall (n = 290-302)	3.67^†	2.20-6.12	1.05	0.64-1.72	1.54^†	1.05-2.25	2.58^†	1.62-4.10	1.60^†	1.03-2.48
Whites only (n = 217-232)	3.69^†	2.18-6.24	1.13	0.68-1.89	1.44	0.93-2.24	2.51^†	1.54-4.09	1.35	0.81-2.23
ARIC (n = 158-170)	4.05^†	2.15-7.64	1.08	0.55-2.12	1.53	0.93-2.52	2.56^†	1.45-4.49	1.41	0.79-2.51
CHS (n = 132-138)	3.16^†	1.31-7.60	0.98	0.47-2.04	1.54	0.86-2.78	2.65^†	1.16-6.09	1.92	0.91-4.04
Incident (n = 253-257)	3.31^†	1.93-5.67	1.05	0.62-1.77	1.33	0.88-2.00	2.28^†	1.39-3.74	1.40	0.88-2.25
Recurrent (n = 37-45)	5.79^†	2.52-13.33	1.07	0.37-3.10	3.33^†	1.60-6.93	4.86^†	2.13-11.08	3.05^†	1.19-7.81
Idiopathic (n = 129-138)	5.91^†	3.34-10.46	1.18	0.62-2.24	1.85^†	1.14-2.99	4.11^†	2.40-7.02	1.97^†	1.09-3.56
Secondary (n = 161-166)	2.02^†	1.01-4.02	0.95	0.50-1.79	1.30	0.80-2.12	1.52	0.81-2.85	1.34	0.77-2.31
DVT (n = 208-216)	3.76^†	2.17-6.53	1.02	0.58-1.78	1.60^†	1.05-2.44	2.63^†	1.58-4.37	1.52	0.94-2.48
PE (n = 44-47)	2.86^†	1.04-7.85	0.79	0.24-2.62	1.03	0.42-2.53	2.21	0.88-5.59	1.24	0.48-3.19
Both (n = 38-42)	4.21^†	1.62-10.93	1.59	0.59-4.23	1.84	0.81-4.17	2.73^†	1.07-6.96	3.68	0.96-14.03

Homozygous plus heterozygous.

P < .05.