Table 4. Age-adjusted OR and 95% CI for... | American Society of Hematology

Table 4.

Age-adjusted OR and 95% CI for idiopathic VTE in relation jointly to factor V Leiden and other factors, LITE

Variable	Factor V Leiden^4-150	No. of events	OR	95% CI
Age
Younger than 65 y	No	58	1.00	Reference
65 y and older	No	52	1.69	0.84-3.41
Younger than 65 y	Yes	20	7.25	3.57-14.76
65 y and older	Yes	8	7.91	2.44-25.65
APC resistant by APC-SR
No	No	85	1.00	Reference
Yes	No	8	0.83	0.38-1.81
No	Yes	5	5.30	1.49-18.81
Yes	Yes	18	5.70	2.85-11.42
HR2^4-150
No	No	98	1.00	Reference
Yes	No	10	1.11	0.54-2.25
No	Yes	24	5.29	2.90-9.64
Yes	Yes	3	16.33	1.68-159
Factor V ag^4-151
Low	No	79	1.00	Reference
High	No	21	1.12	0.71-2.09
Low	Yes	13	5.05	2.29-11.15
High	Yes	13	11.49	4.21-31.35

Variable	Factor V Leiden^4-150	No. of events	OR	95% CI
Age
Younger than 65 y	No	58	1.00	Reference
65 y and older	No	52	1.69	0.84-3.41
Younger than 65 y	Yes	20	7.25	3.57-14.76
65 y and older	Yes	8	7.91	2.44-25.65
APC resistant by APC-SR
No	No	85	1.00	Reference
Yes	No	8	0.83	0.38-1.81
No	Yes	5	5.30	1.49-18.81
Yes	Yes	18	5.70	2.85-11.42
HR2^4-150
No	No	98	1.00	Reference
Yes	No	10	1.11	0.54-2.25
No	Yes	24	5.29	2.90-9.64
Yes	Yes	3	16.33	1.68-159
Factor V ag^4-151
Low	No	79	1.00	Reference
High	No	21	1.12	0.71-2.09
Low	Yes	13	5.05	2.29-11.15
High	Yes	13	11.49	4.21-31.35

Ag indicates antigen.

Heterozygous or homozygous.

Low factor V is in the lower 4 quintiles; high is in the upper quintile.