Proapoptotic synergism of different HA14-1:PD184352 ratios in AML cell lines
| HA14-1:PD184352 ratio . | Combination index* . | ||
|---|---|---|---|
| OCI-AML3 . | HL-60 . | KG1 . | |
| 2:1 | 0.34 ± 0.03 | 0.41 ± 0.1 | N/A |
| 10:1 | 0.46 ± 0.01 | 0.41 ± 0.1 | 1.31 ± 0.1 |
| 20:1 | 0.47 ± 0.01 | 0.41 ± 0.1 | N/A |
| HA14-1:PD184352 ratio . | Combination index* . | ||
|---|---|---|---|
| OCI-AML3 . | HL-60 . | KG1 . | |
| 2:1 | 0.34 ± 0.03 | 0.41 ± 0.1 | N/A |
| 10:1 | 0.46 ± 0.01 | 0.41 ± 0.1 | 1.31 ± 0.1 |
| 20:1 | 0.47 ± 0.01 | 0.41 ± 0.1 | N/A |
N/A indicates not available.
Average ± SD of the CI values obtained at the ED50, ED75, and ED90.