Multivariate regression: LFS, relapse, and TRM
| Variable . | LFS RR . | 95% Confidence interval (CI) . | P . | Relapse RR . | 95% CI . | P . | TRM RR . | 95% CI . | P . | Favorable . |
|---|---|---|---|---|---|---|---|---|---|---|
| Patient age 15 y and older | 1.67 | 1.16, 2.39 | .006 | — | — | — | 2.00 | 1.33, 3.02 | .0009 | Younger patient |
| Duration of CR1 6 months and longer | 0.54 | 0.36, 0.80 | .002 | 0.37 | 0.18, 0.74 | .005 | — | — | — | Longer duration |
| Duration of CR1 12 months and longer | — | — | — | — | — | — | 0.62 | 0.41, 0.94 | .02 | Longer duration |
| Known HLA match | 1.0 | — | — | — | — | — | 1.0 | — | — | Baseline |
| Potential HLA match | 1.28 | 0.78, 2.12 | .33 | — | — | — | 1.53 | 0.84, 2.79 | .17 | — |
| HLA mismatch | 1.85 | 1.35, 2.52 | ≤ .0001 | — | — | — | 2.46 | 1.68, 3.61 | ≤ .0001 | HLA match |
| Donor age, decades | — | — | — | 0.95 | 0.92, 0.99 | .006 | — | — | — | Older donor |
| Karnofsky score 90 or more | 0.62 | 0.41, 0.95 | .03 | — | — | — | 0.47 | 0.36, 0.92 | .02 | Karnofsky score 90 or more |
| WBC count more than 17.7 × 109/L | 1.13 | 1.04, 1.23 | .002 | 1.27 | 1.13, 1.42 | < .0001 | — | — | — | Lower WBC count |
| Variable . | LFS RR . | 95% Confidence interval (CI) . | P . | Relapse RR . | 95% CI . | P . | TRM RR . | 95% CI . | P . | Favorable . |
|---|---|---|---|---|---|---|---|---|---|---|
| Patient age 15 y and older | 1.67 | 1.16, 2.39 | .006 | — | — | — | 2.00 | 1.33, 3.02 | .0009 | Younger patient |
| Duration of CR1 6 months and longer | 0.54 | 0.36, 0.80 | .002 | 0.37 | 0.18, 0.74 | .005 | — | — | — | Longer duration |
| Duration of CR1 12 months and longer | — | — | — | — | — | — | 0.62 | 0.41, 0.94 | .02 | Longer duration |
| Known HLA match | 1.0 | — | — | — | — | — | 1.0 | — | — | Baseline |
| Potential HLA match | 1.28 | 0.78, 2.12 | .33 | — | — | — | 1.53 | 0.84, 2.79 | .17 | — |
| HLA mismatch | 1.85 | 1.35, 2.52 | ≤ .0001 | — | — | — | 2.46 | 1.68, 3.61 | ≤ .0001 | HLA match |
| Donor age, decades | — | — | — | 0.95 | 0.92, 0.99 | .006 | — | — | — | Older donor |
| Karnofsky score 90 or more | 0.62 | 0.41, 0.95 | .03 | — | — | — | 0.47 | 0.36, 0.92 | .02 | Karnofsky score 90 or more |
| WBC count more than 17.7 × 109/L | 1.13 | 1.04, 1.23 | .002 | 1.27 | 1.13, 1.42 | < .0001 | — | — | — | Lower WBC count |