Tumor characteristics in relation to numbers of active caspase 3–positive H/RS cells
| Characteristic . | Active caspase 3–positive H/RS cells (%) . | P . | |
|---|---|---|---|
| ≤ 5% (n = 41)† . | > 5% (n = 22)3-150 . | ||
| P53 | |||
| Negative | 20 | 3 | — |
| Positive | 19 | 19 | .004 |
| P21 | |||
| Negative | 7 | 0 | — |
| Positive | 28 | 18 | .04 |
| Procaspase 3 | |||
| Negative | 9 | 0 | — |
| Positive | 21 | 17 | .01 |
| Activated CTLs | |||
| < 15% | 25 | 17 | — |
| ≥ 15% | 10 | 1 | .05 |
| Characteristic . | Active caspase 3–positive H/RS cells (%) . | P . | |
|---|---|---|---|
| ≤ 5% (n = 41)† . | > 5% (n = 22)3-150 . | ||
| P53 | |||
| Negative | 20 | 3 | — |
| Positive | 19 | 19 | .004 |
| P21 | |||
| Negative | 7 | 0 | — |
| Positive | 28 | 18 | .04 |
| Procaspase 3 | |||
| Negative | 9 | 0 | — |
| Positive | 21 | 17 | .01 |
| Activated CTLs | |||
| < 15% | 25 | 17 | — |
| ≥ 15% | 10 | 1 | .05 |
P values were determined by χ2analysis.
Not all patients were tested because of the absence of enough material for additional immunohistochemical analysis.