Characteristics of dense granules of normal, C3H/HeSnJash/ash and a/a, ash/ash platelets as determined by fluorescence microscopy of mepacrine-labeled platelets
| . | Granules/platelet . | Flashes/platelet . | Flashes/granule . |
|---|---|---|---|
| C3H/HeSnJ +/+ | 5.08 ± .23 (50) | 4.10 ± .25 (64) | 0.81 |
| C3H/HeSnJash/ash | 4.00 ± .25 (61)* | 0.065 ± .03 (61)* | 0.02* |
| C57BL/6J +/+ | 4.96 ± .31 (25) | 3.88 ± .36 (25) | 0.78 |
| a/a, ash/ash | 5.06 ± .29 (49) | 3.61 ± .40 (49) | 0.71 |
| . | Granules/platelet . | Flashes/platelet . | Flashes/granule . |
|---|---|---|---|
| C3H/HeSnJ +/+ | 5.08 ± .23 (50) | 4.10 ± .25 (64) | 0.81 |
| C3H/HeSnJash/ash | 4.00 ± .25 (61)* | 0.065 ± .03 (61)* | 0.02* |
| C57BL/6J +/+ | 4.96 ± .31 (25) | 3.88 ± .36 (25) | 0.78 |
| a/a, ash/ash | 5.06 ± .29 (49) | 3.61 ± .40 (49) | 0.71 |
Values represent the mean ± SEM of determinations on the number of individual platelets in parentheses. These platelets were derived from 3 separate mice for each genotype.
P ≤ .001.