Characteristics of patients with ITP
| Patient no./ age,y /sex . | Duration of ITP . | Plt counts in 3 mo before study (× 109/L) . | Previous bleeding episodes . | Splenectomy (time after surgery) . | Previous therapy* . | Current therapy . |
|---|---|---|---|---|---|---|
| 1/37/M | 5 y 10 mo | 1-14 | Ecchymoses, petechiae | Yes (5 y 9 mo) | Azathioprine, cyclophosphamide, cyclosporine, methotrexate, danazol, ascorbic acid, IVIG, vincristine, platelet transfusion, interferon α-2b, colchicine, dapsone | Prednisone, ascorbic acid |
| 2/61/F | 9 y 10 mo | 5-17 | Ecchymoses, gingival | No | Azathioprine | Prednisone |
| 3/67/F | 7 y | 11-25 | — | No | Chinese medicine (Kamikihito) | None |
| 4/57/M | 8 y 6 mo | 6-8 | Ecchymoses, petechiae | Yes (8 y 1 mo) | Azathioprine, cyclophosphamide, cyclosporine, interferon, danazol, ascorbic acid, vincristine, dapsone | Prednisone, ascorbic acid |
| Patient no./ age,y /sex . | Duration of ITP . | Plt counts in 3 mo before study (× 109/L) . | Previous bleeding episodes . | Splenectomy (time after surgery) . | Previous therapy* . | Current therapy . |
|---|---|---|---|---|---|---|
| 1/37/M | 5 y 10 mo | 1-14 | Ecchymoses, petechiae | Yes (5 y 9 mo) | Azathioprine, cyclophosphamide, cyclosporine, methotrexate, danazol, ascorbic acid, IVIG, vincristine, platelet transfusion, interferon α-2b, colchicine, dapsone | Prednisone, ascorbic acid |
| 2/61/F | 9 y 10 mo | 5-17 | Ecchymoses, gingival | No | Azathioprine | Prednisone |
| 3/67/F | 7 y | 11-25 | — | No | Chinese medicine (Kamikihito) | None |
| 4/57/M | 8 y 6 mo | 6-8 | Ecchymoses, petechiae | Yes (8 y 1 mo) | Azathioprine, cyclophosphamide, cyclosporine, interferon, danazol, ascorbic acid, vincristine, dapsone | Prednisone, ascorbic acid |
ITP indicates idiopathic thrombocytopenic purpura; Plt, platelet; and IVIG, intravenous immunoglobulin.
All patients had ITP refractory to initial steroid therapy.