Numbers of circulating monocytes and DCs in MM patients and healthy donors
| Subjects . | WBC . | Monocytes . | Myeloid DC . | Plasmacytoid DC . |
|---|---|---|---|---|
| MM patients at diagnosis (n = 7) | 7328 ± 2000* | 304 ± 95 | 4.7 ± 4.2 | 3.7 ± 3.8 |
| MM patients with advanced disease (n = 18) | 7150 ± 3200 | 284 ± 130 | 8.9 ± 6.2 | 3.1 ± 2.9 |
| Normal donors | 6552 ± 2300 | 391.1 ± 94.1† | 17 ± 6.3† | 12.1 ± 3.2† |
| Subjects . | WBC . | Monocytes . | Myeloid DC . | Plasmacytoid DC . |
|---|---|---|---|---|
| MM patients at diagnosis (n = 7) | 7328 ± 2000* | 304 ± 95 | 4.7 ± 4.2 | 3.7 ± 3.8 |
| MM patients with advanced disease (n = 18) | 7150 ± 3200 | 284 ± 130 | 8.9 ± 6.2 | 3.1 ± 2.9 |
| Normal donors | 6552 ± 2300 | 391.1 ± 94.1† | 17 ± 6.3† | 12.1 ± 3.2† |
Twenty-five MM patients and 17 healthy subjects were analyzed as described in “Materials and methods.”
Results are expressed as the mean number of cells ± SD/μL of whole PB.
Data from the 3 groups were considered significantly different when P < .05. P = .011 for monocytes, .003 for myeloid DCs, and .0002 for plasmacytoid DCs when healthy donors were compared with MM patients either at diagnosis or with advanced disease. No differences were found when the two groups of patients were compared.