Cloning efficiency of CD34+ cells in the presence and absence of IL-6
| Cytokine stimuli . | CFU-DC . | CFU-M . |
|---|---|---|
| G + T | 0.4 ± 0.2 | 0.6 ± 0.3 |
| G + T + IL-6 | 0.08 ± 0.063-150 | 0.7 ± 0.1 |
| G + T + S + F | 1.1 ± 0.4 | 0.9 ± 0.4 |
| G + T + S + F + IL-6 | 0.1 ± 0.33-150 | 1.1 ± 0.3 |
| Cytokine stimuli . | CFU-DC . | CFU-M . |
|---|---|---|
| G + T | 0.4 ± 0.2 | 0.6 ± 0.3 |
| G + T + IL-6 | 0.08 ± 0.063-150 | 0.7 ± 0.1 |
| G + T + S + F | 1.1 ± 0.4 | 0.9 ± 0.4 |
| G + T + S + F + IL-6 | 0.1 ± 0.33-150 | 1.1 ± 0.3 |
Results are presented as the mean ± SD of 5 different experiments. Cloning efficiency is indicated by the number of colonies scored after 14 days of culture × 100 CD34+cells plated.
Addition of IL-6 inhibited CFU-DC growth (P< .05).