Table 4. GM-progenitors from wild-type... | American Society of Hematology

Table 4.

GM-progenitors from wild-type and G-CSF-deficient mice

Genotype	Total no. of GM-CFC/50 000 BM cells	No. of GM-CFC/50 000 BM cells after pulse exposure of BM cells to³H-TdR^4-150	Percent of GM-progenitors in S-phase	No. of cells/colony
Wild-type	86.0 ± 5.5	63.8 ± 8.0	25.8 ± 1.6	1 259 ± 77
G-CSF^−/−	45.0 ± 7.3^4-151	22.3 ± 5.0	50.6 ± 2.8^4-151	434 ± 64^4-151

Genotype	Total no. of GM-CFC/50 000 BM cells	No. of GM-CFC/50 000 BM cells after pulse exposure of BM cells to³H-TdR^4-150	Percent of GM-progenitors in S-phase	No. of cells/colony
Wild-type	86.0 ± 5.5	63.8 ± 8.0	25.8 ± 1.6	1 259 ± 77
G-CSF^−/−	45.0 ± 7.3^4-151	22.3 ± 5.0	50.6 ± 2.8^4-151	434 ± 64^4-151

F4-150

BM cells were pulse exposed to ³H-TdR prior to plating on methylcellulose medium in the presence of 10 ng/mL GM-CSF as described in “Materials and methods.” Data are represented as mean ± SEM (n = 6).

F4-151

P < .05 (G-CSF^−/− versus wild type).

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