Associations between MBL2 HYA infection stratified according to presence or absence of coding mutations
| Sample group . | No.HYA+ . | No.HYA− . | Major infection whenHYA+, no. (%) . | Major infection whenHYA−, no. (%) . | P . | OR (95% CI) . |
|---|---|---|---|---|---|---|
| Recipients without coding mutation (HYA/A), n = 55 | 40 | 15 | 16 (40) | 13 (87) | .001 | 0.09 (0.02-0.47) |
| Recipients with coding mutation (HYA/O), n = 38 | 16 | 22 | 7 (45) | 17 (77) | .04 | 0.23 (0.06-0.93) |
| Donors without coding mutation (HYA/A), n = 52 | 40 | 12 | 15 (37) | 8 (67) | .07 | 0.30 (0.08-1.17) |
| Donors with coding mutation (HYA/O), n = 38 | 14 | 24 | 9 (64) | 22 (92) | .03 | 0.16 (0.03-1.0) |
| Sample group . | No.HYA+ . | No.HYA− . | Major infection whenHYA+, no. (%) . | Major infection whenHYA−, no. (%) . | P . | OR (95% CI) . |
|---|---|---|---|---|---|---|
| Recipients without coding mutation (HYA/A), n = 55 | 40 | 15 | 16 (40) | 13 (87) | .001 | 0.09 (0.02-0.47) |
| Recipients with coding mutation (HYA/O), n = 38 | 16 | 22 | 7 (45) | 17 (77) | .04 | 0.23 (0.06-0.93) |
| Donors without coding mutation (HYA/A), n = 52 | 40 | 12 | 15 (37) | 8 (67) | .07 | 0.30 (0.08-1.17) |
| Donors with coding mutation (HYA/O), n = 38 | 14 | 24 | 9 (64) | 22 (92) | .03 | 0.16 (0.03-1.0) |
Data regarding HYA and infection has been stratified according to the presence or absence of MBL2 coding mutations. HYA is associated with infection in recipients with and without coding mutations. Similar trends are seen for donor genotype.