Table 2.

Results from our study: NRAS andKRAS2 mutations in cases of MGUS, MM, P-PCL, and HMCL

StatusNRAS mutations (%)KRAS2 mutations (%)
MGUS 1/9‡ 0/9  
MM, P-PCL at diagnosis 10/40 (25)2-153 15/43 (35) 
Relapse   
 Medullary* 4/62-155 0/6 
 Extramedullary† 0/5 5/5 
HMCL 4/152-154 4/15 
StatusNRAS mutations (%)KRAS2 mutations (%)
MGUS 1/9‡ 0/9  
MM, P-PCL at diagnosis 10/40 (25)2-153 15/43 (35) 
Relapse   
 Medullary* 4/62-155 0/6 
 Extramedullary† 0/5 5/5 
HMCL 4/152-154 4/15 

MGUS represents monoclonal gammopathy of undetermined significance; P-PCL, primary plasma cell leukemia; and HMCL, human myeloma cell line.

*

P < .061.

†

P = .008.

‡

One case of N61.

F2-153

Eight cases of N61.

F2-155

Three cases of N61.

F2-154

One case of N61.

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