Proliferation and mitotic indices, CD10, Bcl-2, p53 expression and plasmacytoid differentiation in FL
| Morphology . | FL 1 . | FL 2 . | FL 3a . | P FL 1/2 vs FL 3a . | FL 3b . | FL 3b + DLBL . | FL 3b ± DLBL . | P FL 1-3a vs FL 3b ± DLBL . | P FL 3a vs FL 3b ± DLBL . |
|---|---|---|---|---|---|---|---|---|---|
| Proliferation median | 20 | 40 | 70 | < .0001 | 85 | 80 | 80 | < .0001 | < .11 |
| (range) | (10-50) | (20-70) | (40-80) | (40-90) | (50-100) | (40-100) | |||
| Mitoses median | 12 | 34 | 54 | < .0001 | 55 | 63 | 58 | < .0001 | < .14 |
| (range) | (3-48) | (10-80) | (22-80) | (20-146) | (31-124) | (20-146) | |||
| CD 10 (%) | 29/29 | 32/33 | 11/11 | < .67 | 3/4 | 5/12 | 8/16 | < .0001 | < .01 |
| (100) | (97) | (100) | (75) | (42) | (50) | ||||
| bcl-2 (%) | 29/29 | 33/33 | 8/11 | = .0001 | 2/4 | 9/12 | 11/16 | < .001 | < .83 |
| (100) | (100) | (73) | (50) | (75) | (69) | ||||
| p53 (%) | 0/29 | 1/33 | 1/11 | < .17 | 0/4 | 5/12 | 5/16 | = .0001 | < .18 |
| (0) | (3) | (9) | (0) | (42) | (31) | ||||
| CIg (%) | 1/29 | 1/33 | 0/11 | < .55 | 3/4 | 4/12 | 7/16 | = .0001 | < .01 |
| (3) | (3) | (0) | (75) | (33) | (44) |
| Morphology . | FL 1 . | FL 2 . | FL 3a . | P FL 1/2 vs FL 3a . | FL 3b . | FL 3b + DLBL . | FL 3b ± DLBL . | P FL 1-3a vs FL 3b ± DLBL . | P FL 3a vs FL 3b ± DLBL . |
|---|---|---|---|---|---|---|---|---|---|
| Proliferation median | 20 | 40 | 70 | < .0001 | 85 | 80 | 80 | < .0001 | < .11 |
| (range) | (10-50) | (20-70) | (40-80) | (40-90) | (50-100) | (40-100) | |||
| Mitoses median | 12 | 34 | 54 | < .0001 | 55 | 63 | 58 | < .0001 | < .14 |
| (range) | (3-48) | (10-80) | (22-80) | (20-146) | (31-124) | (20-146) | |||
| CD 10 (%) | 29/29 | 32/33 | 11/11 | < .67 | 3/4 | 5/12 | 8/16 | < .0001 | < .01 |
| (100) | (97) | (100) | (75) | (42) | (50) | ||||
| bcl-2 (%) | 29/29 | 33/33 | 8/11 | = .0001 | 2/4 | 9/12 | 11/16 | < .001 | < .83 |
| (100) | (100) | (73) | (50) | (75) | (69) | ||||
| p53 (%) | 0/29 | 1/33 | 1/11 | < .17 | 0/4 | 5/12 | 5/16 | = .0001 | < .18 |
| (0) | (3) | (9) | (0) | (42) | (31) | ||||
| CIg (%) | 1/29 | 1/33 | 0/11 | < .55 | 3/4 | 4/12 | 7/16 | = .0001 | < .01 |
| (3) | (3) | (0) | (75) | (33) | (44) |