Table 1.

Compete remission rates with gemtuzumab ozogamicin (GO) according to use of interleukin 11 (IL-11)

Cytogenetic findingGO without
IL-11*
GO with
IL-11
Total
Normal 2/9 (22) 7/11 (64)  9/20 (45) 
−5/−7 0/7 0/8   0/15 
Other abnormal 0/10 2/6 (33)  2/16 (13) 
Total 2/26 9/25 11/51 (22) 
Cytogenetic findingGO without
IL-11*
GO with
IL-11
Total
Normal 2/9 (22) 7/11 (64)  9/20 (45) 
−5/−7 0/7 0/8   0/15 
Other abnormal 0/10 2/6 (33)  2/16 (13) 
Total 2/26 9/25 11/51 (22) 

Values are numbers (%) of patients.

*

Two of 20 patients with acute myeloid leukemia (AML), neither of 2 with refractory anemia (RA) with excess of blasts in transformation (RAEB-t), and none of 4 with RA with excess blasts (RAEB).

Seven of 17 patients with AML, 1 of 4 with RAEB-t, and 1 of 4 with RAEB.

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